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Evaluating cumulative risk assessment for environmental justice: a community case study.

机译:评估环境正义的累积风险评估:社区案例研究。

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摘要

A key feature of cumulative risk assessment (CRA) is the ability to estimate differential health risks from environmental exposures within populations. Identifying populations at increased risk from environmental exposures is the first step toward mitigating such risks as required by the fair treatment mandate of environmental justice. CRA methods remain under development except for a limited application in pesticide regulations. The goals of this research were to advance CRA methods and to test their application in a community case study. We compared cumulative risk and health assessments for South and Southwest Philadelphia communities. The analysis found positive correlations between cumulative risk and mortality measurements for total mortality in Whites and non-Whites when we conducted the risk assessment using a multi-end point toxicological database developed for this project. Cumulative risk scores correlated positively with cause-specific mortality in non-Whites. Statistically significant increases in total and respiratory mortality rates were associated with incremental increases in the hazard ratio cumulative risk scores, with ranges of 2-6% for total and 8-23% for respiratory. Regression analyses controlled for percent non-White population and per capita income, indicating that risk scores represent an environmental effect on health independent of race and income. This case study demonstrated the successful application of CRA at the community level. CRA adds a health dimension to pollutant concentrations to produce a more comprehensive understanding of environmental inequities that can inform decision making. CRA is a viable tool to identify high-risk areas and to guide surveillance, research, or interventions.
机译:累积风险评估(CRA)的一项关键功能是能够根据人群内部环境暴露估算出不同的健康风险。确定环境暴露带来的风险增加的人群,是减轻环境正义的公平对待授权所要求的此类风险的第一步。除农药法规中的有限应用外,CRA方法仍在开发中。这项研究的目标是改进CRA方法并在社区案例研究中测试其应用。我们比较了费城南部和西南社区的累积风险和健康评估。当我们使用为此项目开发的多点毒理学数据库进行风险评估时,分析发现了白人和非白人的总死亡率与累积风险与死亡率测量之间存在正相关关系。累积风险评分与非白人的特定原因死亡率呈正相关。总体死亡率和呼吸道死亡率的统计上显着增加与危险比累积风险得分的增加相关,总危险度范围为2-6%,呼吸活动范围为8-23%。回归分析控制了非白人人口百分比和人均收入,表明风险分数代表对健康的环境影响,而与种族和收入无关。此案例研究证明了CRA在社区一级的成功应用。 CRA在污染物浓度中增加了健康方面的内容,以便对环境不公平现象有更全面的了解,从而可以为决策提供依据。 CRA是确定高风险区域并指导监视,研究或干预的可行工具。

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