首页> 美国卫生研究院文献>Environmental Health Perspectives >Hair analysis does not support hypothesized arsenic and chromium exposure from drinking water in Woburn Massachusetts.
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Hair analysis does not support hypothesized arsenic and chromium exposure from drinking water in Woburn Massachusetts.

机译:头发分析不支持马萨诸塞州沃本市饮用水中假定的砷和铬暴露。

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摘要

We hypothesized that residents of Woburn, Massachusetts, had been exposed to as much as 70 microg/l of arsenic (As) and 240 microg/l of chromium (Cr) in drinking water from municipal supply wells G and H. To test this hypothesis, we measured the concentrations of As and Cr in 82 hair samples donated by 56 Woburn residents. Thirty-six samples were cut between 1964 and 1979, the period during which wells G and H were in operation. The remainder were cut either before 1964 (1938-1963; n = 26) or after 1979 (1982-1994; n = 20). Washed hair samples were analyzed by instrumental neutron activation. Exposure to the well water--measured as access--was estimated using well pumping records and a model of the Woburn water distribution system. Our results show that access to wells G and H water was not significantly correlated (95% confidence interval) with As and Cr concentrations measured in the hair of Woburn residents, but As concentrations have declined significantly over the last half century. Linear regression of As concentrations (micrograms per gram) upon year of hair cut and access to wells G and H water yielded a standard coefficient for year of -0. 0074 +/- 0.0017 (standard error; p = 2.5 -multiple- 10(-5)) and -0.12 +/- 0.10 (p = 0.22) for access. The r2 value for the model was 0.19. The geometric mean concentrations (geometric standard deviation) of As and Cr in the hair of residents who had access (i.e., relative access estimate >0) to wells G and H water (n = 27) were 0.14 (2.6) and 2.29 (1.8) microg/g, respectively; the geometric mean concentrations of As and Cr in all of the hair samples from residents who did not have access (1938-1994; n = 55) were 0.13 (3.0) and 2.19 (2.0) microg/g, respectively.
机译:我们假设马萨诸塞州沃本市的居民从市政供水井G和H的饮用水中接触了多达70微克/升的砷(As)和240微克/升的铬(Cr)。为检验这一假设,我们测量了56位Woburn居民捐赠的82个头发样本中的As和Cr浓度。在1964年至1979年间G和H井投入运营的那段时间里,共切割了36个样品。其余部分在1964年之前(1938-1963; n = 26)或1979年之后(1982-1994; n = 20)被削减。通过仪器中子活化分析洗过的头发样品。使用井抽记录和Woburn配水系统的模型来估算井水的暴露量(以进水量衡量)。我们的结果表明,进入沃恩镇居民的头发中的砷和铬浓度与进入水井G和H的水量没有显着相关(95%置信区间),但在过去半个世纪中,砷的浓度已显着下降。剪发一年以及进入井G和H水后,砷浓度(每克微克)的线性回归得出-0年的标准系数。 0074 +/- 0.0017(标准误差; p = 2.5乘以10(-5))和-0.12 +/- 0.10(p = 0.22)用于访问。该模型的r2值为0.19。可以使用(即,相对使用率估计值> 0)G和H水井(n = 27)的居民头发中的As和Cr的几何平均浓度(几何标准偏差)为0.14(2.6)和2.29(1.8) )分别为microg / g;在所有无法接触的居民中(1938-1994; n = 55),所有头发样本中As和Cr的几何平均浓度分别为0.13(3.0)和2.19(2.0)microg / g。

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