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Completing the molecular investigation into the HIV outbreak at Glenochil prison.

机译:完成对格莱诺基尔监狱艾滋病毒暴发的分子调查。

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摘要

In a molecular investigation into the outbreak of HIV in Glenochil during the first 6 months of 1993, we previously demonstrated that 13 out of the 14 HIV positive inmates were infected with a virtually identical strain, and discounted 2 others as potential sources. Here we investigate a further 8 potential contacts and 4 potential sources which were identified in the companion paper. We were able to examine viral sequence from all but one of these 12 and results have revealed them to be distinct both from each other and the original 14. Thus, despite an intensive follow-up investigation, we have been unable to identify any further HIV infections that might have been part of the 1993 outbreak. It is possible that persons who were infected at that time remain undetected; however this and the companion report strongly suggest that if this were the case the likely numbers would be few.
机译:在1993年头6个月对格莱诺基尔爆发的艾滋病毒的分子研究中,我们先前证明,在14名艾滋病毒阳性囚犯中,有13名感染了几乎相同的毒株,而另2名是潜在的感染源。在这里,我们调查了在随附文件中确定的另外8个潜在联系人和4个潜在来源。我们能够检查除这12个病毒中的一个病毒之外的所有病毒序列,结果显示它们彼此之间和原始的14个病毒中都不同。因此,尽管进行了深入的后续调查,我们仍无法发现任何进一步的HIV感染可能是1993年爆发的一部分。当时被感染的人有可能未被发现;但是,这和随附的报告强烈建议,如果是这种情况,则可能的人数将很少。

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