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A Nonredundant Phosphopantetheinyl Transferase PptA Is a Novel Antifungal Target That Directs Secondary Metabolite Siderophore and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity

机译：非冗余磷酸泛肽基转移酶PptA是一种新型抗真菌靶标可指导烟曲霉中的次级代谢产物铁载体和赖氨酸的生物合成并且对致病性至关重要

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期刊名称 mBio
作者
Anna Johns; Daniel H. Scharf; Fabio Gsaller; Hella Schmidt; Thorsten Heinekamp; Maria Straßburger; Jason D. Oliver; Mike Birch; Nicola Beckmann; Katharine S. Dobb; Jane Gilsenan; Bharatkumar Rash; Elaine Bignell; Axel A. Brakhage; Michael J. Bromley;
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作者单位

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年(卷),期 2017(8),4
年度 2017
页码 e01504-16
总页数 22
原文格式 PDF
正文语种
中图分类微生物学;
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1. A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity [J] . Anna Johns, Daniel H. Scharf, Fabio Gsaller, MBio . 2017,第4期

机译：非冗余的磷酸泛肽基转移酶PptA是一种新型的抗真菌靶标，它指导烟曲霉中的次级代谢产物，铁载体和赖氨酸的生物合成，并且对致病性至关重要
2. Author Correction: Phosphopantetheinyl transferase (Ppt)-mediated biosynthesis of lysine, but not siderophores or DHN melanin, is required for virulence of Zymoseptoria tritici on wheat [J] . Mark C. Derbyshire, Amir Mirzadi Gohari, Rahim Mehrabi, Scientific reports. . 2019,第1期

机译：作者校正：磷酸乙醚转移酶（PPT）介导的赖氨酸的生物合成，但不是磷光酯或Dhn黑色素，是小麦唑唑类麦芽素的毒力所必需的
3. Phosphopantetheinyl transferase (Ppt)-mediated biosynthesis of lysine, but not siderophores or DHN melanin, is required for virulence of Zymoseptoria tritici on wheat [J] . Mark C. Derbyshire, Amir Mirzadi Gohari, Rahim Mehrabi, Scientific reports. . 2018,第1期

机译：小麦中枯草芽孢杆菌的毒力需要磷酸泛素甲酰基转移酶（Ppt）介导的赖氨酸生物合成，而不需要铁载体或DHN黑色素。
4. Lysine Acetylome in Streptomyces roseosporus Reveals the Roles of Lysine Acetylation in Regulating Biosynthesis of Secondary Metabolites [C] . Guojian Liao, Longxiang Xie, Xiaojun Peng, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：rosepyces玫瑰孢菌素中的赖氨酸乙酰物揭示了赖氨酸乙酰化在调节次级代谢物生物合成中的作用
5. Studies on the biosynthesis of prenylated indole secondary metabolites from Aspergillus versicolor and Aspergillus sp.; and A novel approach to tumor specific drug delivery: Use of a naphthyridine drug linker with a DNA hairpin [D] . Finefield, Jennifer M. 2011

机译：杂色曲霉和曲霉菌的烯丙基化吲哚二级代谢产物的生物合成研究；和肿瘤特异性药物递送的新方法：萘啶药物接头与DNA发夹的结合使用
6. Phosphopantetheinyl transferase (Ppt)-mediated biosynthesis of lysine but not siderophores or DHN melanin is required for virulence of Zymoseptoria tritici on wheat [O] . Mark C. Derbyshire, Amir Mirzadi Gohari, Rahim Mehrabi, -1

机译：小麦中枯草芽孢杆菌的毒力是必需的由磷酸泛肽基转移酶（Ppt）介导的赖氨酸生物合成而不需要铁载体或DHN黑色素。
7. A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity [O] . Anna Johns, Daniel H. Scharf, Fabio Gsaller, 2017

机译：非冗余磷酸泛酰巯基乙胺基转移酶，ppta，是一种新型抗真菌靶标，可指导烟曲霉中的次生代谢产物，铁载体和赖氨酸生物合成，对致病性至关重要

A Nonredundant Phosphopantetheinyl Transferase PptA Is a Novel Antifungal Target That Directs Secondary Metabolite Siderophore and Lysine Biosynthesis in Aspergillus fumigatus and Is Critical for Pathogenicity

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