Skin Rash and Fever of Unknown Origin A Diagnostic Challenge

摘要

We report a clinical case of adult-onset Still’s disease. In addition to the imaging features of the case, the following aspects are also briefly described: clinical presentation (prolonged fever associated with migratory polyarthritis and skin rash), treatment performed (resort to anti-inflammatory and corticoid), and clinical evolution of the patient after having performed the adult-onset.The treatment was found to be appropriate as the patient presented a favourable clinical evolution.LEARNING POINTS class="unordered" style="list-style-type:disc">Skin manifestations are associated with systemic diseases.Persistent febrile syndromes typically occur in young age.Adult-onset Still’s disease is generally considered as a diagnosis of exclusion, as it presents with a combination of non-specific symptoms. class="kwd-title">Keywords: Adult-onset Still’s disease, skin rash, fever of unknown origin class="head no_bottom_margin" id="__sec2title">INTRODUCTIONFirst described in 1971, adult-onset Still’s disease (AOSD) is a rare multisystem disorder considered as a complex autoinflammatory syndrome characterised by quotidian fevers, arthritis and an evanescent rash^[,]. The aetiology of AOSD is unknown. Both genetic factors and a variety of infectious triggers have been suggested as important, but there has been no conclusive evidence to date^[,].