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Antimicrobial prescribing in long-term care facilities: a nationwide point-prevalence study Slovenia 2016

机译:长期护理机构中的抗菌药物处方:一项全国性点流行性研究斯洛文尼亚2016年

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摘要

Residents in long-term care are at high risk of infections because of their old age and many related health problems that lead to frequent antibiotic prescribing. The aim of the study was to assess antibiotic use in Slovenian long-term care facilities (LTCFs). The point-prevalence study was conducted between April and June 2016. Online questionnaires were sent to all Slovenian LTCFs. Eighty (68.4%) of the 117 LTCFs contacted, caring for 13,032 residents (70.6% of all Slovenian LTCF residents), responded to the survey. On the day of the study, the mean antibiotic prevalence per LTCF was 2.4% (95% confidence interval: 1.94–2.66). Most (70.2%) of the residents taking antibiotics were female. Most residents were being treated for respiratory tract (42.7%) or urinary tract (33.3%) infections. Co-amoxiclav and fluoroquinolones were the most frequently prescribed antibiotics (41.0% and 22.3% respectively). Microbiological tests were performed for 5.2% of residents receiving antibiotics. Forty nine (19.8%) residents receiving antibiotics were colonised with multidrug-resistant bacteria (MDR). Antibiotic use in Slovenian LTCFs is not very high, but most prescribed antibiotics are broad-spectrum. Together with low use of microbiological testing and high prevalence of colonisation with MDR bacteria the situation is worrisome and warrants the introduction of antimicrobial stewardship interventions.
机译:长期护理的居民由于年老以及许多相关的健康问题导致经常开抗生素处方,因此感染的风险很高。该研究的目的是评估斯洛文尼亚长期护理机构(LTCF)中的抗生素使用情况。该点流行度研究于2016年4月至6月进行。在线问卷已发送给所有斯洛文尼亚LTCF。接受调查的117个LTCF中有80个(68.4%)照顾了13,032名居民(占斯洛文尼亚LTCF全部居民的70.6%)。在研究当天,每个LTCF的平均抗生素患病率为2.4%(95%置信区间:1.94-2.66)。服用抗生素的大多数居民(70.2%)是女性。大多数居民正在接受呼吸道感染(42.7%)或泌尿道感染(33.3%)的治疗。复方阿莫西非和氟喹诺酮类药物是最常用的抗生素(分别为41.0%和22.3%)。对5.2%的接受抗生素治疗的居民进行了微生物学测试。接受抗生素的四十九名(19.8%)居民被多药耐药菌(MDR)定殖。斯洛文尼亚LTCF的抗生素使用率不是很高,但是大多数处方抗生素是广谱的。再加上微生物检测的使用率低和MDR细菌定植的普遍性,这种情况令人担忧,需要引入抗微生物管理干预措施。

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