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Vitamin D improves the content of TGF-β and IGF-1 in intervertebral disc of diabetic rats

机译：维生素D改善糖尿病大鼠椎间盘中TGF-β和IGF-1的含量

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摘要

Objective: The contents of transforming growth factor-β and insulin-like growth factor-1 in disc of diabetic rats were measured at three different periods after injected with 1,25-Dihydroxyvitamin D3, and compared with that in normal rats. The significance of content changes was also discussed.

机译：目的：在糖尿病大鼠椎间盘中分别注射1,25-二羟基维生素D3后3个时期，测定其转化生长因子-β和胰岛素样生长因子-1的含量，并与正常大鼠进行比较。还讨论了内容更改的重要性。

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期刊名称 Experimental Biology and Medicine
作者
Ji-long An; Wei Zhang; Jian Zhang; Li-chao Lian; Yong Shen; Wen-yuan Ding;
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作者单位

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年(卷),期 2017(242),12
年度 2017
页码 1254–1261
总页数 8
原文格式 PDF
正文语种
中图分类医学史 ;
关键词
Vitamin D transforming growth factor-β insulin-like growth factor-1 STZ calcitriol diabetes;

机译：维生素D;转化生长因子β;胰岛素样生长因子-1;STZ;骨化三醇;糖尿病;

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专利

1. Vitamin D improves the content of TGF-beta and IGF-1 in intervertebral disc of diabetic rats [J] . An Ji-long, Zhang Wei, Zhang Jian, Experimental Biology and Medicine: Journal of the Society for Experimental Biology and Medicine . 2017 ,第12期

机译：维生素D在糖尿病大鼠椎间盘中改善TGF-β和IGF-1的含量
2. Quantitative analysis of exogenous IGF-1 administration of intervertebral disc through intradiscal injection [J] . HuangC.-Y., TravascioF., GuW.Y. Journal of Biomechanics . 2012 ,第7期

机译：椎间盘内注射外源性IGF-1椎间盘给药的定量分析
3. High rat food vitamin E content improves nerve function in streptozotocin-diabetic rats. [J] . van Dam-PS, Bravenboer B, van Asbeck-BS, European Journal of Pharmacology: An International Journal . 1999 ,第3期

机译：大鼠食物中维生素E含量高，可改善链脲佐菌素糖尿病大鼠的神经功能。
4. EFFECT OF TGF-β3 ON THE GENE EXPRESSION OF INTERVERTEBRAL DISC CELLS IN 3D PELLET CULTURES [C] . Houseman C., Scro M., Belverud S., ASME Bioengineering Conference . 2010

机译：TGF-β3对3D颗粒培养物中椎间盘细胞基因表达的影响
5. Altered and restored function after reduced nucleus pulposus glycosaminoglycan content in the rat lumbar intervertebral disc [D] . Boxberger, John I. 2009

机译：大鼠腰椎间盘髓核糖胺聚糖含量减少后功能改变和恢复
6. Quantitative Analysis of Exogenous IGF-1 Administration of Intervertebral Disc Through Intradiscal Injection [O] . C.-Y Huang, F. Travascio, W.Y. Gu -1

机译：通过盘阴液进行外源IGF-1给药椎间盘的定量分析
7. Content changes in TGF-β and IGF-1 and their significance in the discs of diabetic rats [O] . Ji-long An 2018

机译：含量变化TGF-β和IGF-1及其在糖尿病大鼠椎间盘中的重要性

Vitamin D improves the content of TGF-β and IGF-1 in intervertebral disc of diabetic rats

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