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Multi-trait Multi-environment Deep Learning Modeling for Genomic-Enabled Prediction of Plant Traits

机译:基于基因组预测的植物性状的多特征多环境深度学习建模

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摘要

Multi-trait and multi-environment data are common in animal and plant breeding programs. However, what is lacking are more powerful statistical models that can exploit the correlation between traits to improve prediction accuracy in the context of genomic selection (GS). Multi-trait models are more complex than univariate models and usually require more computational resources, but they are preferred because they can exploit the correlation between traits, which many times helps improve prediction accuracy. For this reason, in this paper we explore the power of multi-trait deep learning (MTDL) models in terms of prediction accuracy. The prediction performance of MTDL models was compared to the performance of the Bayesian multi-trait and multi-environment (BMTME) model proposed by , which is a multi-trait version of the genomic best linear unbiased prediction (GBLUP) univariate model. Both models were evaluated with predictors with and without the genotype×environment interaction term. The prediction performance of both models was evaluated in terms of Pearson’s correlation using cross-validation. We found that the best predictions in two of the three data sets were found under the BMTME model, but in general the predictions of both models, BTMTE and MTDL, were similar. Among models without the genotype×environment interaction, the MTDL model was the best, while among models with genotype×environment interaction, the BMTME model was superior. These results indicate that the MTDL model is very competitive for performing predictions in the context of GS, with the important practical advantage that it requires less computational resources than the BMTME model.
机译:多性状和多环境数据在动植物育种计划中很常见。但是,缺少更强大的统计模型,可以利用性状之间的相关性来提高基因组选择(GS)情况下的预测准确性。多特征模型比单变量模型更复杂,并且通常需要更多的计算资源,但它们是首选的,因为它们可以利用特征之间的相关性,这在很多时候都有助于提高预测准确性。因此,在本文中,我们从预测准确性的角度探讨了多特征深度学习(MTDL)模型的功能。将MTDL模型的预测性能与提出的贝叶斯多特征和多环境(BMTME)模型的性能进行了比较,后者是基因组最佳线性无偏预测(GBLUP)单变量模型的多特征版本。两种模型都使用带有和不带有基因型×环境相互作用项的预测变量进行评估。使用交叉验证,根据皮尔逊相关性评估了两个模型的预测性能。我们发现,在BMTME模型下可以找到三个数据集中的两个的最佳预测,但是总的来说,两个模型BTMTE和MTDL的预测都是相似的。在没有基因型×环境相互作用的模型中,MTDL模型是最好的,而在具有基因型×环境相互作用的模型中,BMTME模型是更好的。这些结果表明,MTDL模型对于在GS上下文中执行预测非常有竞争力,具有重要的实际优势,即与BMTME模型相比,它需要更少的计算资源。

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