首页> 美国卫生研究院文献>Gastroenterology Research and Practice >Bypass during Liver Transplantation: Anachronism or Revival? Liver Transplantation Using a Combined Venovenous/Portal Venous Bypass—Experiences with 163 Liver Transplants in a Newly Established Liver Transplantation Program
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Bypass during Liver Transplantation: Anachronism or Revival? Liver Transplantation Using a Combined Venovenous/Portal Venous Bypass—Experiences with 163 Liver Transplants in a Newly Established Liver Transplantation Program

机译:肝移植中的旁路:陈旧还是复兴?使用静脉/门静脉旁路联合进行肝移植-在新建立的肝移植计划中使用163种肝移植的经验

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摘要

Introduction. The venovenous/portal venous (VVP) bypass technique has generally become obsolete in liver transplantation (LT) today. We evaluated our experience with 163 consecutive LTs that used a VVP bypass. Patients and Methods. The liver transplant program was started in our center in 2010. LTs were performed using an extracorporal bypass device. Results. Mean operative time was 269 minutes and warm ischemic time 43 minutes. The median number of transfusion of packed cells and plasma was 7 and 14. There was no intraoperative death, and the 30-day mortality was 3%. Severe bypass-induced complications did not occur. Discussion. The introduction of a new LT program requires maximum safety measures for all of the parties involved. Both surgical and anaesthesiological management (reperfusion) can be controlled very reliably using a VVP bypass device. Particularly when using marginal grafts, this approach helps to minimise both surgical and anaesthesiological complications in terms of less volume overload, less use of vasopressive drugs, less myocardial injury, and better peripheral blood circulation. Conclusion. Based on our experiences while establishing a new liver transplantation program, we advocate the reappraisal of the extracorporeal VVP bypass.
机译:介绍。如今,静脉/门静脉(VVP)旁路技术在肝移植(LT)中已普遍淘汰。我们评估了使用VVP旁路的163个连续LT的经验。患者和方法。肝移植计划于2010年在我们中心开始。LTs使用体外旁路装置进行。结果。平均手术时间为269分钟,热缺血时间为43分钟。堆积细胞和血浆的输血中位数为7和14。无术中死亡,30天死亡率为3%。没有发生严重的旁路并发症。讨论。引入新的LT计划要求对所有相关方采取最大的安全措施。使用VVP旁路设备可以非常可靠地控制手术和麻醉管理(再灌注)。尤其是在使用边缘移植物时,这种方法有助于减少手术量和麻醉并发症,这是因为减少了容量负荷,减少了血管加压药的使用,减少了心肌损伤,改善了外周血循环。结论。在建立新的肝移植计划时,基于我们的经验,我们主张对体外VVP旁路进行重新评估。

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