首页> 美国卫生研究院文献>Genome Biology >Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors

【2h】

Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors

机译：DNA甲基化和拷贝数变化对乳腺肿瘤中miRNA表达的个体和综合影响

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundThe global effect of copy number and epigenetic alterations on miRNA expression in cancer is poorly understood. In the present study, we integrate genome-wide DNA methylation, copy number and miRNA expression and identify genetic mechanisms underlying miRNA dysregulation in breast cancer.

机译：背景技术拷贝数和表观遗传学改变对癌症中miRNA表达的总体影响知之甚少。在本研究中，我们整合了全基因组DNA甲基化，拷贝数和miRNA表达，并确定了乳腺癌中miRNA失调的遗传机制。

著录项

期刊名称 Genome Biology
作者
Miriam Ragle Aure; Suvi-Katri Leivonen; Thomas Fleischer; Qian Zhu; Jens Overgaard; Jan Alsner; Trine Tramm; Riku Louhimo; Grethe I Grenaker Alnæs; Merja Perälä; Florence Busato; Nizar Touleimat; Jörg Tost; Anne-Lise Børresen-Dale; Sampsa Hautaniemi; Olga G Troyanskaya; Ole Christian Lingjærde; Kristine Kleivi Sahlberg; Vessela N Kristensen;
展开▼
作者单位

展开▼
年(卷),期 2013(14),11
年度 2013
页码 R126
总页数 20
原文格式 PDF
正文语种
中图分类生物学;
关键词

相似文献

外文文献
中文文献
专利

1. Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors [J] . Miriam Ragle Aure, Suvi-Katri Leivonen, Thomas Fleischer, Genome Biology . 2013,第11期

机译：DNA甲基化和拷贝数变化对乳腺肿瘤中miRNA表达的个体和综合影响
2. Expression and DNA methylation alterations of seven cancer-associated 3p genes and their predicted regulator miRNAs (miR-129-2, miR-9-1) in breast and ovarian cancers [J] . Pronina Irina V., Loginov Vitaly I., Burdennyy Alexey M., Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function . 2016,第1aPta3期

机译：乳腺癌和卵巢癌中7个与癌症相关的3p基因及其预测的调节性miRNA（miR-129-2，miR-9-1）的表达和DNA甲基化变化
3. Combined analysis of gene expression, DNA copy number, and mutation profiling data to display biological process anomalies in individual breast cancers. [J] . Weiwei Shi, Balint Balazs, Balazs Gy?rffy, Breast cancer research and treatment. . 2014,第3期

机译：基因表达，DNA拷贝数和突变图谱数据的组合分析可显示单个乳腺癌的生物学过程异常。
4. A Computational Method to Predict DNA Copy Number Alterations from Gene Expression Data in Tumor Cases [C] . Huimin Geng, Wing C. Chan, Hesham H. Ali Hawaii International Conference on System Sciences . 2009

机译：预测肿瘤病例中基因表达数据的DNA拷贝数改变的计算方法
5. Epidemiology of Childhood Germ Cell Tumors (GCT): Epigenome-Wide Methylation, Differential MiRNA Expression, and Catchment Quality of the CCRN [D] . Musselman, Jessica Rutledge Bruce 2013

机译：儿童生殖细胞肿瘤（GCT）的流行病学：表观基因组的甲基化，差异miRNA表达和CCRN的流域质量。
6. Integrative analysis of DNA copy number DNA methylation and gene expression in multiple myeloma reveals alterations related to relapse [O] . Patryk Krzeminski, Luis A. Corchete, Juan L. García, 2016

机译：对多发性骨髓瘤中DNA拷贝数DNA甲基化和基因表达的综合分析揭示了与复发相关的改变
7. Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors [O] . Miriam Aure, Suvi-Katri Leivonen, Thomas Fleischer, 2013

机译：DNA甲基化和拷贝数变化对乳腺肿瘤中miRNA表达的个体和综合影响

Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors

摘要

著录项

相似文献

相关主题

期刊订阅