Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates

摘要

BackgroundBurkholderia thailandensis is a non-pathogenic environmental saprophyte closely related to Burkholderia pseudomallei, the causative agent of the often fatal animal and human disease melioidosis. To study B. thailandensis genomic variation, we profiled 50 isolates using a pan-genome microarray comprising genomic elements from 28 Burkholderia strains and species.