Identification of expressed genes linked to malignancy of human colorectal carcinoma by parametric clustering of quantitative expression data

摘要

BackgroundIndividual human carcinomas have distinct biological and clinical properties: gene-expression profiling is expected to unveil the underlying molecular features. Particular interest has been focused on potential diagnostic and therapeutic applications. Solid tumors, such as colorectal carcinoma, present additional obstacles for experimental and data analysis.