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Complementation and Noncomplementation among Nonallelic Mutations Altering Development in SCHIZOPHYLLUM COMMUNE

机译:非等位基因突变之间的互补和非互补改变SCHIZOPHYLLUM COMMUNE的发育

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摘要

Mutations resistant to compounds that alter the development of Schizophyllum commune (cyclic adenosine monophosphate, caffeine and imidazole) were selected. These mutations defined four genes, car (cAMP resistance), caf-1 and caf-2 (caffeine resistance) and imr (imidazole resistance). The mutations were found to be noncomplementing in certain pairs when tested against each other and against two previously isolated developmental mutations, B-con and sep (septateless), in fully compatible, forced heterokaryons. The pattern of complementation in fully compatible diploids showed noncomplementation only between allelic mutations, except for one case, imr vs. car.
机译:选择了对改变裂殖壶菌属(Schizophyllum commune)发育的化合物具有抗性的突变(环状单磷酸腺苷,咖啡因和咪唑)。这些突变定义了四个基因,car(cAMP抗性),caf-1和caf-2(咖啡因抗性)和imr(咪唑抗性)。当在完全兼容的强迫异核体中彼此相对以及与两个先前分离的发育突变B-con和sep(无分隔)进行测试时,发现该突变在某些对中不互补。完全兼容的二倍体中的互补模式仅在等位基因突变之间显示出非互补,只有一种情况是imr vs. car。

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