首页> 美国卫生研究院文献>Global Spine Journal >Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report
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Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report

机译:耐甲氧西林金黄色葡萄球菌在免疫功能正常的患者中肺结核性肉芽肿的超级感染引起的胸椎椎间盘炎:一例报告

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摘要

>Study Design Case report. >Objective To describe a very rare case of an immunocompetent man who underwent surgery for thoracic spondylodiscitis caused by methicillin-resistant Staphylococcus aureus (MRSA) that developed as a superinfection of a pulmonary tuberculous granuloma. >Methods Posterior decompression and pedicle screw vertebral fixation were followed by T5–T6 anterior somatotomy with implant of an expandable mesh and lateral plating as symptoms worsened. During the anterior approach, an atypical resection of the left lower lobe was also performed. >Results A tuberculous granuloma was detected on histology. Ziehl-Neelsen stain confirmed the diagnosis. Culture also detected MRSA. >Conclusions Early medical management is the first choice for spondylodiscitis to eradicate the infection and alleviate pain. Immobilization of the affected spine segments can protect the patient from vertebral collapse and from the appearance of neurologic deficits. Surgery is suggested if there are compressive effects on the spinal cord, spinal epidural abscess, vertebral collapse, and deformity. We decided to remove the abscess and to restore the anterior column using an anterior approach. Moreover, in this case, an anterior approach allowed us to identify the etiology of the lesion and to determine the best chemotherapy regimen.
机译:>研究设计案例报告。 >目的描述一名非常有免疫能力的人,该人因甲氧西林耐药性金黄色葡萄球菌(MRSA)引起的胸椎系统疾病而发展成外科病,该病发展为肺结核性肉芽肿的过度感染。 >方法后路减压和椎弓根螺钉固定后,再进行T5–T6前躯体切开术,并植入可扩张网片和侧板作为症状加重。在前入路过程中,还进行了左下叶的非典型切除。 >结果组织学检查发现有结核性肉芽肿。 Ziehl-Neelsen染色证实了诊断。文化也检测到MRSA。 >结论早期医疗是脊椎盘炎根除感染和减轻疼痛的首选方法。固定受影响的脊柱节段可以保护患者免受椎骨塌陷和神经功能缺损的影响。如果对脊髓,硬脊膜硬膜脓肿,椎体塌陷和畸形有压缩作用,建议进行手术。我们决定去除脓肿并使用前路入路修复前柱。此外,在这种情况下,前路手术使我们能够确定病变的病因并确定最佳的化疗方案。

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