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Revised Tubiana’s Staging System for Assessment of Disease Severity in Dupuytren’s Disease—Preliminary Clinical Findings

机译:经修订的Tubiana分期系统用于评估Dupuytren病的疾病严重程度-初步临床发现

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摘要

There are few objective staging systems to assess severity of Dupuytren’s disease (DD). Previous methods to assess severity of DD were based primarily on the degree of contracture of an affected digit measured using a goniometer. Nonetheless, this method of assessment alone may be incomplete, and other factors should be considered. White (n = 92) patients diagnosed with DD from northwest of England were assessed for DD. Objective criteria for evaluating severity incorporated quantified variables. The revised severity stage was correlated to a known staging system of DD (Tubiana’s staging system) which measures total flexion deformity for a single affected digit. Total revised severity staging scores ranged between 4 and 53 (mean = 18.7) and revealed significant positive correlation to Tubiana’s original staging system (r2 = 0.8, p < 0.001). There was significant difference between severity staging scores in those with a positive family history compared to those without (p < 0.01). In current practice, often, the degree of contracture in an affected digit is used solely as a measure of disease severity. Additional objective clinical information may provide useful prognostic indices for disease progression as well as postoperative outcome.
机译:几乎没有客观的分期系统来评估Dupuytren病(DD)的严重性。评估DD严重程度的先前方法主要基于使用测角计测量的受影响手指的挛缩程度。但是,仅凭这种评估方法可能还不完善,还应考虑其他因素。评估了英格兰西北部诊断为DD的白人(n = 92)患者的DD。评估严重程度的客观标准纳入了量化变量。修订后的严重程度阶段与已知的DD分期系统(Tubiana的分期系统)相关,该系统可测量单个受影响手指的总屈曲畸形。修订后的严重度分期总评分范围在4到53之间(平均18.7),并显示出与Tubiana原始分期系统显着正相关(r 2 = 0.8,p <0.001)。有阳性家族史的患者与没有阳性家族史的患者相比,严重程度分值之间存在显着差异(p <0.01)。在当前的实践中,通常,受影响手指的挛缩程度仅用作疾病严重程度的量度。其他客观的临床信息可能会为疾病的进展以及术后结果提供有用的预后指标。

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