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Different patterns of association between education and wealth with non-fatal myocardial infarction in Tehran Iran: A population-based case-control study

机译:伊朗德黑兰教育与财富与非致命性心肌梗死之间的不同关联模式:基于人群的病例对照研究

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摘要

>Background: Myocardial Infarction (MI) is a main cause of death and disability worldwide, which involves a number of genetic, physiopathologic and socio-economic determinants. The aim of this study was to assess the patterns of association between education, wealth and some other risk factors with non-fatal MI in Tehran population. >Methods: Data derived from a second round of large cross-sectional study, Urban HEART-2, conducted in Tehran in 2011. Out of 118542 participants, all 249 self-reported incident cases of nonfatal MI were selected as the case group. A number of 996, matched on age and sex, were selected as controls. Principle component analysis (PCA) was used to calculate wealth index and logistic regression model to assess relations between the study variables. >Results: Mean (SD) age of participants was 60.25 (12.26) years. A total of 870 (69.9%) of the study subjects were men. Education, wealth status, family violence, hypertension and diabetes were observed as independent predictors of non-fatal MI. Overall, as the level of education increased, the odds of non-fatal MI decreased (p<0.001). We observed an almost J-shaped association between wealth status and non-fatal MI. No significant associations were found between marital status, BMIand current smoking with non-fatal MI (p<0.05).>Conclusion: We found different patterns of association between education and wealth with nonfatalMI among Tehran adults. Lower risk of non-fatal MI is linked to high educated groups whereas economicallymoderate group has the lowest risk of non-fatal MI occurrence.
机译:>背景:心肌梗塞(MI)是全球范围内死亡和残疾的主要原因,它涉及许多遗传,生理病理和社会经济因素。这项研究的目的是评估德黑兰人口中非致命性心肌梗死的教育,财富和其他一些危险因素之间的关联模式。 >方法:数据来源于2011年在德黑兰进行的第二轮大型横断面研究Urban Urban2。从118542名参与者中,选择了249例自我报告的非致命性MI事件作为案例组。选择年龄和性别匹配的996个作为对照。主成分分析(PCA)用于计算财富指数和逻辑回归模型,以评估研究变量之间的关系。 >结果:参与者的平均(SD)年龄为60.25(12.26)岁。共有870名(69.9%)研究对象为男性。教育,财富状况,家庭暴力,高血压和糖尿病是非致命性MI的独立预测因子。总体而言,随着教育水平的提高,非致命性心肌梗死的几率降低(p <0.001)。我们观察到财富状况和非致命性心肌梗死之间几乎呈J型联系。婚姻状况和BMI之间未发现显着关联和目前非致命性MI吸烟(p <0.05)。>结论:我们发现教育和财富与非致命性之间存在不同的关联模式德黑兰成年人中的MI。非致命性MI的较低风险与受过高等教育的人群有关,而在经济上中度组发生非致命性MI的风险最低。

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