首页> 美国卫生研究院文献>Gut >Microprocessor controlled movement of liquid gastric contentusing sequential neural electrical stimulation
【2h】

Microprocessor controlled movement of liquid gastric contentusing sequential neural electrical stimulation

机译:微处理器控制液体胃内容物的运动使用顺序神经电刺激

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Background—Gastric electrical stimulation has been attempted for several years with little success.
Aims—To determine whether movement of liquid gastric content could be achieved using microprocessor controlled sequential electrical stimulation.
Methods—Eight anaesthetised dogs underwent laparotomy and implantation of four sets of bipolar stainless steel wire electrodes. Each set consisted of two to six electrodes (10×0.25 mm, 3 cm apart) implanted circumferentially. The stomach was filled with water and the process of gastric emptying was monitored. Artificial contractions were produced using microprocessor controlled phase locked bipolar four second trains of 50 Hz, 14 V (peak to peak) rectangular voltage. In four of the dogs four force transducers were implanted close to each circumferential electrode set. In one gastroparetic patient the effect of direct electrical stimulation was determined at laparotomy.
Results—Using the above stimulating parameters circumferential gastric contractions were produced which were artificially propagated distally by phase locking the stimulating voltage. Averaged stimulated gastric emptying times were significantly shorter than spontaneus emptying times (t1/2 6.7 (3.0) versus 25.3 (12.9) minutes, p<0.01). Gastric electrical stimulation of the gastroparetic patient at operation produced circumferential contractions.
Conclusions—Microprocessor controlled electricalstimulation produced artificial peristalsis and notably accelerated themovement of liquid gastric content.

Keywords:gastric electrical stimulation; gastric motility
机译:背景技术已经尝试了几年的电刺激,但收效甚微。
目的-确定是否可以使用微处理器控制的顺序电刺激来实现胃液含量的运动。
方法-对八只麻醉的狗进行剖腹手术并植入四组双极不锈钢丝电极。每组包括两到六个电极(10×0.25 mm,相距3 cm),它们沿圆周方向植入。胃中充满水并监测胃排空的过程。使用微处理器控制的50 Hz,14 V(峰到峰)矩形电压的锁相双极四秒列产生人工收缩。在四只狗中,有四个力传感器植入到每个圆周电极组附近。在一名胃轻瘫患者中,在剖腹手术中确定了直接电刺激的效果。
结果-使用上述刺激参数,产生了胃周收缩,这些胃收缩是通过锁相刺激电压而向远端人工传播的。平均刺激胃排空时间明显短于自发性胃排空时间(t1 / 2 6.7(3.0)vs 25.3(12.9)分钟,p <0.01)。胃轻瘫患者在手术时的胃电刺激产生圆周收缩。
结论—微处理器控制的电气刺激产生了人工蠕动,并显着加速了液体胃内容物的运动。

关键字:胃电刺激;胃动力

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号