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Clinical Outcomes of Surgically Managed Spontaneous Tumors in 114 Client-owned Dogs

机译:114只自养犬手术治疗自发性肿瘤的临床结果

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摘要

Medical records of 139 tumors from 114 dogs that underwent surgery from May 2010 through March 2015 were retrospectively reviewed. Among 114 dogs, females (64.9%) were significantly more common than males (35.1%) (p<0.05). Dogs aged 6 to 10 years were more presented than non-tumor patients, however, there was no significant difference. The mean age (±SD) was 10.3±3.0 years. Although we found no significant difference of breed predisposition, the most common breed was Maltese (19.3%), followed by Shih-Tzu (14.0%), and Yorkshire terrier (13.2%). Proportional morbidity ratios (PMRs) of mammary gland, oral cavity, and skin tumors were high in Poodles, Yorkshire terriers, and Golden retrievers, respectively. Mammary gland (36.0%) was the most common site, followed by skin and soft tissues (12.2%), oral cavity (10.8%), and digestive organs (8.6%), but there was no significant difference. The objectives of surgery were curative surgery (86.2%), biopsy (4.9%), and palliative surgery (6.5%). In this study, 123 of 139 tumors had histopathological diagnoses. Adenocarcinoma was the most common type (n=24), followed by adenoma (n=17), soft tissue sarcoma (n=13), benign mixed tumor (n=5), and others (n=64). Recurrence or suspected metastasis was identified in 26 dogs. Median survival times of malignant mammary gland tumors, skin and subcutaneous tumors, and splenic tumors were 1,563.0±1,201.7, 469, and 128 days, respectively.
机译:回顾性分析了从2010年5月至2015年3月接受手术的114只狗的139例肿瘤的医疗记录。在114只狗中,雌性(64.9%)比雄性(35.1%)更为常见(p <0.05)。与非肿瘤患者相比,年龄在6至10岁的狗更多,但无显着差异。平均年龄(±SD)为10.3±3.0岁。尽管我们没有发现品种倾向的显着差异,但最常见的品种是马耳他人(19.3%),其次是西施犬(14.0%)和约克夏犬(13.2%)。贵宾犬,约克夏犬和金毛猎犬的乳腺,口腔和皮肤肿瘤的比例发病率(PMR)分别较高。乳腺(36.0%)是最常见的部位,其次是皮肤和软组织(12.2%),口腔(10.8%)和消化器官(8.6%),但没有显着差异。手术的目标是治愈性手术(86.2%),活检(4.9%)和姑息手术(6.5%)。在这项研究中,139个肿瘤中有123个得到了组织病理学诊断。腺癌是最常见的类型(n = 24),其次是腺瘤(n = 17),软组织肉瘤(n = 13),良性混合肿瘤(n = 5)和其他类型(n = 64)。在26只狗中鉴定出复发或疑似转移。恶性乳腺肿瘤,皮肤和皮下肿瘤以及脾脏肿瘤的中位生存时间分别为1,563.0±1,201.7、469和128天。

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