Safety and efficacy of Bivalirudin with Glycoprotein IIb/IIIa for high-risk percutaneous coronary intervention

摘要

AimsThe aim of the study was to assess the safety and efficacy of Bivalirudin + Glycoprotein (Gp) IIb/IIIa inhibitor as compared to unfractionated Heparin (UFH) + Gp IIb/IIIa inhibitor in high risk patients undergoing elective percutaneous coronary intervention (PCI). The primary end point was time to sheath removal and ambulation where as peri-procedure myocardial damage, access site bleeding and major adverse cardiac events (MACE) rates were secondary end points.