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Prevalence of Hearing Loss in High Risk Infants of Mediocre Socio-economic Background at Around One Year of Age and Their Correlation with Risk Factors

机译:中等社会经济背景的高危婴儿在一年左右的年龄中听力损失的患病率及其与危险因素的相关性

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摘要

The present study tried to determine the hearing threshold by brainstem evoked response audiometry (BERA) in the high-risk infants from a mediocre socio-economic background at around 1 year of age and correlate different risk factors with hearing loss. BERA was done on 127 infants of 6–18 months age of which 87 were high risk. All were given monaural acoustic stimulus using Cz-M1/M2 Montage. Based on the appearance of wave V at minimum stimulus intensity, hearing threshold in decibels (dB) of each ear was determined. To study the association of the individual risk factor with hearing loss multiple logistic regression test was applied. Taking BERA threshold for ‘Pass’ as ≤40 dBnHL, out of 87 high risk infants 10.34 % (n = 9) had bilateral severe to profound hearing loss, 17.24 % (n = 15) had bilateral mild to moderate hearing loss and 12.64 % (n = 11) had impaired hearing in one ear. All of the control group infants had normal hearing threshold of 30 dBnHL. Twenty major risk factors were identified in the whole study group at an average of 2.3 factors per infant. Twelve factors were examined for correlation using Odd’s ratio (OR) with >40 dBnHL threshold as the outcome variable. Factors with very high OR were family history of deafness, Ototoxic drugs and Cranio-facial abnormality followed by others. High risk infants have a persistent and definitive risk of hearing loss prompting early intervention.
机译:本研究试图通过脑干诱发反应测听(BERA)来确定社会经济背景中等的高危婴儿在1岁左右时的听力阈值,并将不同的危险因素与听力损失相关联。在127个6-18个月大的婴儿中进行了BERA,其中87个是高危人群。所有患者均使用Cz-M1 / M2 Montage给予单声道听觉刺激。根据最小刺激强度下的V波出现,确定每只耳朵的听力阈值,以分贝(dB)为单位。为了研究个体危险因素与听力损失的相关性,应用了多重逻辑回归检验。以87例高危婴儿的BERA门槛为``通过''为≤40 dBnHL,在10.34%(n = 9)的双侧重度至重度听力下降中,有17.24%(n = 15)的双侧轻度至中度听力下降和12.64% (n = 11)一只耳朵的听力受损。所有对照组婴儿的正常听力阈值为30 dBnHL。在整个研究组中,确定了二十个主要危险因素,每个婴儿平均2.3个因素。使用> 40 dBnHL阈值作为结果变量的奇数比(OR),检查了十二个因素的相关性。 OR很高的因素是耳聋的家族史,耳毒性药物和颅面异常,其次是其他因素。高危婴儿有持续且明确的听力损失风险,因此需要早期干预。

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