Metabolic engineering of Mortierella alpina for arachidonic acid production with glycerol as carbon source

摘要

BackgroundAlthough some microorganisms can convert glycerol into valuable products such as polyunsaturated fatty acids, the yields are relative low due primarily to an inefficient assimilation of glycerol. Mortierella alpina is an oleaginous fungus which preferentially uses glucose over glycerol as the carbon source for fatty acid synthesis.