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Nanotechnology: A Revolution in Cancer Diagnosis

机译:纳米技术:癌症诊断的一场革命

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摘要

Nanotechnology has brought revolution in cancer detection and treatment. It has capability to detect even a single cancerous cell in vivo and deliver the highly toxic drugs to the cancerous cells. Nanoshells, carbon nanotubes, quantum dots, supermagnetic nanoparticles, nano wires, nanodiamonds, dandrimers, and recently synthesized nanosponges are some of the materials used for cancer detection. Using specific cross linkers, such as specific antibodies against cancer cells individual cancer cells can be located. With the aid of a novel set of lipid-coated, targeted quantum dots a method for quantifying multiple specific biomarkers on the surfaces of individual cancer cells was also developed. This approach to quantitative biomarker detection stands to improve the histopathology methods used to diagnosis pancreatic and other cancers and enable the development of methods to spot cancer cells circulating in the blood stream. Certain nano materials can also deliver cancer drugs at the site so the drug toxicity can also be reduced.
机译:纳米技术带来了癌症检测和治疗的革命。它具有甚至在体内检测单个癌细胞并将高毒性药物递送至癌细胞的能力。纳米壳,碳纳米管,量子点,超磁性纳米颗粒,纳米线,纳米金刚石,树枝状聚合物和最近合成的纳米海绵是用于癌症检测的一些材料。使用特异性交联剂,例如针对癌细胞的特异性抗体,可以定位单个癌细胞。借助于一组新的脂质涂覆的靶向量子点,还开发了一种用于定量单个癌细胞表面上多个特异性生物标志物的方法。这种定量生物标志物检测的方法有望改善用于诊断胰腺癌和其他癌症的组织病理学方法,并使能够发现血液中循环的癌细胞的方法得以发展。某些纳米材料也可以在该部位递送抗癌药物,因此也可以降低药物毒性。

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