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Long-term prognosis and related factors towards patients with acute pulmonary thromboembolism

机译:急性肺血栓栓塞患者的长期预后及相关因素

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摘要

This study aims to investigate the long-term prognosis and the affecting factors towards the patients with acute pulmonary thromboembolism (APTE). The clinical data of 903 PTE patients, diagnosed by the spiral CT pulmonary angiography (CTPA) or lung ventilation perfusion scanning when hospitalized in the Second Hospital of Hebei Medical University from January 1998 to December 2013, were collected, among who 548 patients were performed the long-term follow-up, and the factors that would affect the prognosis were statistically analyzed. The univariate analysis showed that many factors would affect the prognosis of PTE. The multivariate non-conditional logistic regression analysis showed that: the relevant factors of re-embolization included the idiopathic pulmonary embolism, RVD, D-dimer positive, anticoagulation treatment < 3 months, post-treatment PASP > 40 mmHg, the relevant factors of death included the D-dimer positive, anticoagulation treatment < 3 months, cTnI positive, post-treatment PASP > 40 mmHg. RVD and post-treatment PASP > 40 mmHg would increase the risk of chronic thromboembolic pulmonary hypertension (CTEPH). The idiopathic pulmonary embolism, RVD, D-dimer positive, anticoagulation treatment < 3 months, cTnI positive and post-treatment PASP > 40 mmHg were the important factors that would affect the long-term prognosis of PTE patients.
机译:本研究旨在探讨急性肺血栓栓塞症(APTE)患者的长期预后及其影响因素。收集1998年1月至2013年12月在河北医科大学第二医院住院的螺旋CT肺血管造影(CTPA)或肺通气灌注扫描诊断的903例PTE患者的临床资料,其中548例患者进行长期随访,并对影响预后的因素进行统计学分析。单因素分析表明,许多因素会影响PTE的预后。多元非条件logistic回归分析表明:再次栓塞的相关因素包括特发性肺栓塞,RVD,D-二聚体阳性,抗凝治疗<3个月,治疗后PASP> 40mmHg,死亡的相关因素包括D-二聚体阳性,抗凝治疗<3个月,cTnI阳性,治疗后PASP> 40 mmHg。 RVD和治疗后PASP> 40 mmHg会增加慢性血栓栓塞性肺动脉高压(CTEPH)的风险。特发性肺栓塞,RVD,D-二聚体阳性,抗凝治疗<3个月,cTnI阳性和治疗后PASP> 40 mmHg是影响PTE患者长期预后的重要因素。

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