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Intranasal Application of Budesonide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Nucleotide-Binding Oligomerization Domain-Like Receptor Family Pyrin Domain-Containing 3 Inflammasome Activation in Mice

机译：布地奈德的鼻内应用通过抑制核苷酸结合寡聚化域样受体家族含有3个炎性体活化的吡喃结构域来减轻脂多糖诱导的急性肺损伤。

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摘要

Aim To investigate the protective effects of budesonide against lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in a murine model and its underlying mechanism.

机译：目的探讨布地奈德对小鼠模型中脂多糖（LPS）诱导的急性肺损伤（ALI）的保护作用及其潜在机制。

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期刊名称 Clinical and Developmental Immunology
作者
Liang Dong; Yu-Hang Zhu; De-Xing Liu; Juan Li; Peng-Cheng Zhao; Yuan-Ping Zhong; Yong-Qin Chen; Wei Xu; Zhao-Qiong Zhu;
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年(卷),期 2019(2019),-1
年度 2019
页码 7264383
总页数 10
原文格式 PDF
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中图分类免疫学;
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专利

1. Intranasal Application of Budesonide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Nucleotide-Binding Oligomerization Domain-Like Receptor Family, Pyrin Domain-Containing 3 Inflammasome Activation in Mice [J] . Liang Dong, Yu-Hang Zhu, De-Xing Liu, Journal of immunology research. . 2019,第1期

机译：通过抑制核苷酸结合的低聚域样受体家族，含吡林结构域的3颗小鼠中的吡林结构域的3种炎症性激活来抑制脂多糖诱导的急性肺损伤的鼻内应用
2. Negative Regulation of Autophagy in Activating Nucleotide-Binding Oligomerization Domain-Like Receptor Family Pyrin Domain-Containing 3 Inflammasomes in the Hippocampus of an Epilepsy Rat Model [J] . Wu Jiamei, Chen Liqiang, Wang Shuo, Nanoscience and Nanotechnology Letters . 2019,第7期

机译：在激活核苷酸结合寡聚化结构域样受体家族吡喃结构域的3种癫痫大鼠模型中的含有3种炎症的阴性调节
3. Rac1 GTPase Inhibition Blocked Podocyte Injury and Glomerular Sclerosis during Hyperhomocysteinemia via Suppression of Nucleotide-Binding Oligomerization Domain-Like Receptor Containing Pyrin Domain 3 Inflammasome Activation [J] . Zhang Q., Conley S.M., Li G., Kidney and blood pressure research . 2019,第4期

机译：Rac1 GTPase抑制高同型半胱氨酸血症期间通过抑制核苷酸结合寡聚化域类似受体包含pyrin域3炎症小体激活来阻止足细胞损伤和肾小球硬化。
4. Rho kinase inhibition attenuates LPS-induced acute lung injury in mice partly through cytoskeletal signaling mechanism [C] . Li Yan, Wu Wei-kang IT in Medicine and Education (ITME), 2011 International Symposium on . 2011

机译：Rho激酶抑制部分通过细胞骨架信号传导机制减轻LPS诱导的小鼠急性肺损伤
5. Traumatic Brain Injury-Induced Acute Lung Injury: Evidence for Activation and Inhibition of a Neural-Respiratory-Inflammasome Axis [D] . Kerr, Nadine A. 2019

机译：创伤性脑损伤诱导的急性肺损伤：激活和抑制神经呼吸 - 炎症轴的证据
6. The Overexpression of Sirtuin1 (SIRT1) Alleviated Lipopolysaccharide (LPS)-Induced Acute Kidney Injury (AKI) via Inhibiting the Activation of Nucleotide-Binding Oligomerization Domain-Like Receptors (NLR) Family Pyrin Domain Containing 3 (NLRP3) Inflammasome [O] . Qiufang Gao, Hengting Zhu 2019

机译：Sirtuin1（SIRT1）的过表达通过抑制包含3（NLRP3）炎性小体的核苷酸结合寡聚化域样受体（NLR）家族Pyrin域的激活而减轻脂多糖（LPS）诱导的急性肾损伤（AKI）。
7. Intranasal Application of Budesonide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Nucleotide-Binding Oligomerization Domain-Like Receptor Family, Pyrin Domain-Containing 3 Inflammasome Activation in Mice [O] . Liang Dong, Yu-Hang Zhu, De-Xing Liu, 2019

机译：通过抑制核苷酸结合的低聚域样受体家族，含吡林结构域的3颗小鼠中的吡林结构域的3种炎症性激活来抑制脂多糖诱导的急性肺损伤的鼻内施用

Intranasal Application of Budesonide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Nucleotide-Binding Oligomerization Domain-Like Receptor Family Pyrin Domain-Containing 3 Inflammasome Activation in Mice

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