Dispersion in porous media in oscillatory flow between flat plates: applications to intrathecal periarterial and paraarterial solute transport in the central nervous system

摘要

BackgroundAs an alternative to advection, solute transport by shear-augmented dispersion within oscillatory cerebrospinal fluid flow was investigated in small channels representing the basement membranes located between cerebral arterial smooth muscle cells, the paraarterial space surrounding the vessel wall and in large channels modeling the spinal subarachnoid space (SSS).