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Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer

机译：鉴定对BRAF野生型和突变型结直肠癌具有放射敏感性的抗癌药

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ObjectivePatients with BRAF-mutant colorectal cancer (CRC) have a poor prognosis. Molecular status is not currently used to select which drug to use in combination with radiotherapy. Our aim was to identify drugs that radiosensitise CRC cells with known BRAF status.

机译：目的患有BRAF突变的结直肠癌（CRC）的患者预后较差。目前尚未使用分子状态来选择将哪种药物与放疗结合使用。我们的目的是鉴定对已知BRAF状态的CRC细胞具有放射敏感性的药物。

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期刊名称 Cancer Biology Medicine
作者
Rebecca Carter; Azadeh Cheraghchi-Bashi; Adam Westhorpe; Sheng Yu; Yasmin Shanneik; Elena Seraia; Djamila Ouaret; Yasuhiro Inoue; Catherine Koch; Jenny Wilding; Daniel Ebner; Anderson J. Ryan; Francesca M. Buffa; Ricky A. Sharma;
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年(卷),期 2019(16),2
年度 2019
页码 234–246
总页数 19
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Radiosensitizer colorectal cancer PARP inhibitor radiotherapy;

机译：放射增敏剂;大肠癌;PARP抑制剂;放疗;
入库时间 2022-08-17 13:15:37

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专利

1. Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer [J] . Rebecca Carter, Azadeh Cheraghchi-Bashi, Adam Westhorpe, 癌症生物学与医学：英文版 . 2019,第002期

机译：鉴定对BRAF野生型和突变型结直肠癌具有放射敏感性的抗癌药
2. Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer [J] . Rebecca Carter, Jenny Wilding, Daniel Ebner, 癌症生物学与医学（英文版） . 2019,第002期

机译：鉴定对BRAF野生型和突变型结直肠癌具有放射敏感性的抗癌药
3. Antisense oligodeoxynucleotide directed against c-myb has anticancer activity and potentiates the antiproliferative effect of conventional anticancer drugs acting by different mechanisms in human colorectal cancer cells. [J] . Abaza MS, Al-Attiyah RJ, Al-Saffar AM, Tumour biology : . 2003,第5期

机译：针对c-myb的反义寡聚脱氧核苷酸具有抗癌活性，并增强了常规抗癌药物通过不同机制作用于人结直肠癌细胞的抗增殖作用。
4. Anticancer effectiveness of polymeric drug nanocarriers on colorectal cancer cells [C] . Wang Jiesheng, Peng Ching-An 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2011

机译：高分子药物纳米载体对结直肠癌细胞的抗癌作用
5. 1. X-ray crystallographic analyses of the gene V protein from Ff bacteriophage, a single-stranded DNA-binding protein, and its Y41 mutants 2. X-ray crystallographic analyses of several anticancer drugs and their interactions with DNA. [D] . Guan, Yue. 1994

机译：1.来自Ff噬菌体的V基因基因，单链DNA结合蛋白及其Y41突变体的X射线晶体学分析。2.几种抗癌药物的X射线晶体学分析及其与DNA的相互作用。
6. Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase [O] . Safiatou T. Coulibaly, Paola Rossolillo, Flore Winter, -1

机译：人类脱氧胞苷激酶的四重突变体对癌细胞的有效敏化作用。
7. Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer [O] . Carter Rebecca, Cheraghchi-Bashi Azadeh, Westhorpe Adam, 2019

机译：鉴定抗癌药的抗刺激性药物 - 野生型和突变结直肠癌

Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer

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