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History of burns: The past, present and the future

机译:烧伤的历史:过去,现在和未来

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摘要

Burn injuries are one of the most common and devastating afflictions on the human body. In this article we look back at how the treatment of burns has evolved over the centuries from a primarily topical therapy consisting of weird and wonderful topical concoctions in ancient times to one that spans multiple scientific fields of topical therapy, antibiotics, fluid resuscitation, skin excision and grafting, respiratory and metabolic care and nutrition. Most major advances in burn care occurred in the last 50 years, spurred on by wars and great fires. The use of systemic antibiotics and topical silver therapy greatly reduced sepsis related mortality. This along with the advent of antiseptic surgical techniques, burn depth classification and skin grafting allowed the excision and coverage of full-thickness burns which resulted in greatly improved survival rates. Advancements in the methods of assessing the surface area of burns paved way for more accurate fluid resuscitation, minimising the effects of shock and avoiding fluid over-loading. The introduction of metabolic care, nutritional support and care of inhalational injuries further improved the outcome of burn patients. We also briefly discuss some future directions in burn care such as the use of cell and pharmalogical therapies.
机译:烧伤是人体最常见的破坏性疾病之一。在本文中,我们回顾了数百年来从传统的局部疗法(包括古怪而奇妙的局部混合疗法)到跨越局部疗法,抗生素,液体复苏,皮肤切除术等多个科学领域的局部疗法的发展历程以及嫁接,呼吸和新陈代谢护理以及营养。在战争和大火的刺激下,烧伤护理领域的大多数重大进步都发生在过去的50年中。使用全身性抗生素和局部银疗法可大大降低败血症相关的死亡率。随着消毒外科技术的出现,烧伤深度分类和植皮,可以切除和覆盖全厚度烧伤,从而大大提高了生存率。评估烧伤表面积的方法的进步为更准确的液体复苏铺平了道路,最大限度地减少了冲击的影响并避免了液体超负荷。代谢护理,营养支持和吸入性伤害护理的引入进一步改善了烧伤患者的预后。我们还将简要讨论烧伤护理的一些未来方向,例如细胞和药物治疗的使用。

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