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Provision of chlamydia testing in a nationwide service offering termination of pregnancy: with data capture to monitor prevalence of infection

机译:在全国范围内提供衣原体检测服务以终止妊娠:通过数据采集来监测感染的发生率

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摘要

>Objectives: To establish a methodology by which all women attending for termination of pregnancy (TOP) at British Pregnancy Advisory Service (BPAS) branches may be approached to participate in Chlamydia trachomatis screening. To examine the feasibility of monitoring C trachomatis prevalence and the impact of charging for screening on the uptake rate in this population. >Methods: Patients attending for TOP at participating BPAS branches were offered a test for chlamydia infection and asked to complete a questionnaire. Urine samples from participants were tested using a nucleic acid amplification test (NAAT). >Results: 1001 women provided a urine sample, a 77% response rate among those participating in the study. Factors significantly associated with taking up chlamydia screening included symptoms, previous TOP, parity, and no previous chlamydial test. Overall prevalence of genital chlamydial infection was 7.5%, with highest age specific prevalences occurring among attendees aged 20–24 years (11.5%) and under 20 years (10.8%). In univariate analysis, chlamydia positivity was significantly associated with respondent age and previous diagnosis with chlamydia. Only 35% of women who had the screening test would have done so had they been asked to pay the £20 clinical, administrative, and laboratory costs of the examination. >Conclusions: We have demonstrated the feasibility of routine chlamydia screening and the potential for prospective prevalence monitoring across the nationwide BPAS service. In most cases the chlamydia result was available within the clinical contact period for the TOP. Charging patients directly for the test could reduce uptake of chlamydia screening to levels unsatisfactory for both the public health and prevalence monitoring purposes.
机译:>目标:建立一种方法,通过该方法,可以联系所有在英国怀孕咨询服务(BPAS)分支机构参加终止妊娠(TOP)的妇女参加沙眼衣原体的筛查。审查监测沙眼衣原体患病率的可行性以及筛查收费对该人群摄取率的影响。 >方法:为参与BPAS分支机构参加TOP的患者提供了衣原体感染测试,并要求他们填写问卷。使用核酸扩增测试(NAAT)对参与者的尿液样本进行了测试。 >结果:1001名妇女提供了尿液样本,参与研究的妇女中有77%的应答率。与衣原体筛查显着相关的因素包括症状,先前的TOP,胎次和未进行衣原体检测。生殖器衣原体感染的总体患病率为7.5%,其中年龄最高的特定患病率发生在20-24岁(11.5%)和20岁以下(10.8%)的参与者中。在单变量分析中,衣原体阳性与应答者年龄和先前诊断为衣原体显着相关。如果要求她们支付20英镑的临床,行政和实验室检查费用,只有35%接受筛查的女性愿意这样做。 >结论:我们已经证明了常规衣原体筛查的可行性以及在全国BPAS服务中进行前瞻性患病率监测的潜力。在大多数情况下,衣原体检测结果可在TOP的临床接触期内获得。直接向患者收费以进行测试可能会将衣原体筛查的摄取降低到公共卫生和患病率监测目的都不能令人满意的水平。

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