Haemodynamic effects of the flavonoid quercetin in rats revisited

摘要

The flavonoid quercetin increased the potency of the α ‐antagonist tamsulosin to reduce phenylephrine‐dependent arterial contractions by 10‐fold. To examine if this supplement–drug interaction luxates hypotensive and orthostatic events , several set of studies were conducted in spontaneously hypertensive (SHR) and normotensive (Wistar Kyoto [WKY]) rats.