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The Concise Guide to Pharmacology 2013/14.: The Concise Guide to Pharmacology 2013/14: Transporters

机译:简明药理指南2013/14 ::简明药理指南2013/14

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摘要

The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (), which provides more detailed views of target and ligand properties. The full contents can be found at .Transporters are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets.It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website , superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and the Guide to Receptors and Channels, providing a permanent, citable, point-in-time record that will survive database updates.
机译:《 2013/14药学简要指南》简要概述了2000多种人类药物靶标的药理特性,并链接到药物靶标及其配体的开放获取知识库(),其中提供了靶标和配体的更详细视图属性。转运蛋白是《指南》所划分的七个主要药理学靶标之一,其他是G蛋白偶联受体,配体门控离子通道,离子通道,催化受体,核激素受体和酶。这些指南提供了术语指导和有关最佳可用药理学工具的摘要信息,以及重要的参考文献和建议,供您进一步阅读。一种新的景观格式具有易于使用的表格来比较相关目标,它是当代至2013年末材料的精简版,在网站上会进行更详细的介绍并不断更新,以取代之前的《受体和通道指南》中提供的数据。它与NC-IUPHAR一起生产,并在适当的情况下提供了官方的IUPHAR分类和人类药物靶标的命名法。它合并了以前在IUPHAR-DB和《受体与通道指南》中分​​别策划和显示的信息,提供了永久,可引用的时间点记录,这些记录将在数据库更新后继续存在。

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