Inhibition of human N‐ and T‐type calcium channels by an ortho‐phenoxyanilide derivative MONIRO‐1

摘要

Background and PurposeVoltage‐gated calcium channels are involved in nociception in the CNS and in the periphery. N‐type (Cav2.2) and T‐type (Cav3.1, Cav3.2 and Cav3.3) voltage‐gated calcium channels are particularly important in studying and treating pain and epilepsy.