首页> 美国卫生研究院文献>British Journal of Pharmacology and Chemotherapy >Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats

【2h】

Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats

机译：全身抑制Rho激酶对糖尿病大鼠血压和肾脏血流动力学的影响

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BACKGROUND AND PURPOSEThe RhoA/Rho associated kinases (ROCK) pathway has been implicated in the pathophysiology of diabetic nephropathy (DN). Early stages of diabetes are associated with renal haemodynamic changes, contributing to later development of DN. However, the role of RhoA/ROCK, known regulators of vascular tone, in this process has not been studied.

机译：背景与目的RhoA / Rho相关激酶（ROCK）通路已被认为与糖尿病肾病（DN）的病理生理有关。糖尿病的早期与肾血流动力学改变有关，从而导致DN的晚期发展。但是，尚未研究RhoA / ROCK（已知的血管紧张度调节剂）在此过程中的作用。

著录项

期刊名称 British Journal of Pharmacology and Chemotherapy
作者
R Komers; TT Oyama; DR Beard; S Anderson;
展开▼
作者单位

展开▼
年(卷),期 2011(162),1
年度 2011
页码 163–174
总页数 12
原文格式 PDF
正文语种
中图分类药学 ;
关键词
diabetic nephropathy RhoA GTPase Rho associated kinase Y27632 fasudil effective renal plasma flow myosin light chain ruboxistaurin;

机译：糖尿病肾病;RhoA GTPase;Rho相关激酶;Y27632;法舒地尔;有效肾血浆流量;肌球蛋白轻链;ruboxistaurin;

相似文献

外文文献
中文文献
专利

1. Effects of p38 mitogen-activated protein kinase inhibition on blood pressure, renal hemodynamics, and renal vascular reactivity in normal and diabetic rats. [J] . Komers R, Schutzer W, Xue H, Translational research: the journal of laboratory and clinical medicine . 2007 ,第6期

机译：p38丝裂原活化蛋白激酶抑制作用对正常和糖尿病大鼠的血压，肾脏血流动力学和肾脏血管反应性的影响。
2. HSC-specific inhibition of Rho-kinase reduces portal pressure in cirrhotic rats without major systemic effects [J] . KleinS., VanBeugeM.M., GranzowM., Journal of Hepatology: The Journal of the European Association for the Study of the Liver . 2012 ,第6期

机译：HSC特异性抑制Rho激酶可降低肝硬化大鼠的门脉压力，而无主要全身作用
3. Effects of statins on renal sodium and water handling: Acute and short-term effects of atorvastatin on renal haemodynamics, tubular function, vasoactive hormones, blood pressure and pulse rate in healthy, normocholesterolemic humans. [J] . Paulsen L, Holm C, Bech JN, Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association . 2008 ,第5期

机译：他汀类药物对肾脏钠和水处理的影响：阿托伐他汀对健康，正常胆固醇血症的人的肾血流动力学，肾小管功能，血管活性激素，血压和脉搏率的急性和短期影响。
4. The effects of acute nitric oxide synthase inhibition on systemic circulation and organ blood flow [C] . Chatpun Surapong, Cabrales Pedro The 5th Biomedical Engineering International Conference. . 2012

机译：急性一氧化氮合酶抑制作用对全身循环和器官血流的影响
5. HEMATOLOGICAL CHANGES IN RESPONSE TO EXPOSURE TO MODERATE ALTITUDES (HEMOGLOBIN, RED BLOOD CELLS, SYSTEMIC BLOOD PRESSURE) [D] . BERRY, MICHAEL JOSEPH. 1983

机译：对中度海拔暴露的血液学变化（血红蛋白，红色血液细胞，系统性血液压力）
6. Effects of high‐sodium intake on systemic blood pressure and vascular responses in spontaneously diabetic WBN/Kob‐Leprfa/fa rats [O] . Yoshiichi Takagi, Haruno Kadowaki, Ikumi Kobayashi, -1

机译：高钠摄入量对自发性糖尿病WBN / Kob-Lepr的全身血压和血管反应的影响fa / fa大鼠
7. Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats [O] . Komers, R, Oyama, TT, Beard, DR, 2010

机译：全身抑制Rho激酶对糖尿病大鼠血压和肾脏血流动力学的影响
8. Nitric Oxide Inhibition in the Rat Improves Blood Pressure and Renal Function During Hypovolemic Shock [R] . Lieberthal, W. , McGarry, A. E. , Sheils, J. , 1991

机译：大鼠一氧化氮抑制在低血容量休克期间改善血压和肾功能

Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats

摘要

著录项

相似文献

相关主题

期刊订阅