Salvianolic acid B suppresses maturation of human monocyte-derived dendritic cells by activating PPARγ

摘要

BACKGROUND AND PURPOSESalvianolic acid B (Sal B), a water-soluble antioxidant derived from a Chinese medicinal herb, is known to be effective in the prevention of atherosclerosis. Here, we tested the hypothesis that the anti-atherosclerotic effect of Sal B might be mediated by suppressing maturation of human monocyte-derived dendritic cells (h-monDC).