Beneficial effects of C36 a novel breaker of advanced glycation endproducts cross-links on the cardiovascular system of diabetic rats

机译：新型糖基化终产物交联剂C36对糖尿病大鼠心血管系统的有益作用

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Background and purpose:Advanced glycation endproducts (AGE) have been implicated in the pathogenesis of diabetic complications, including diabetic cardiovascular dysfunctions. 3-benzyloxycarbonylmethyl-4-methyl-thiazol-3-ium bromide (C36), a novel AGE breaker, was investigated for its beneficial effects on the cardiovascular system of diabetic rats.

机译：背景与目的：高级糖基化终产物（AGE）已被认为与糖尿病并发症（包括糖尿病性心血管功能障碍）的发病机制有关。研究了一种新型AGE破乳剂3-苄氧基羰基甲基-4-甲基噻唑-3-溴化铵（C36）对糖尿病大鼠心血管系统的有益作用。

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期刊名称 British Journal of Pharmacology and Chemotherapy
作者
G Cheng; L-L Wang; L Long; H-Y Liu; H Cui; W-S Qu; S Li;
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作者单位

展开▼
年(卷),期 2007(152),8
年度 2007
页码 1196–1206
总页数 11
原文格式 PDF
正文语种
中图分类药学;
关键词
C36 AGE cardiovascular diabetes;

机译：C36;年龄;心血管;糖尿病;

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专利

1. C16, a novel advanced glycation endproduct breaker, restores cardiovascular dysfunction in experimental diabetic rats [J] . Gang CHENG, Li-li WANG, Wen-sheng QU, Acta Pharmacologica Sinica . 2005,第12期

机译：C16，一种新型的先进糖基化终末产物抑制剂，可恢复实验性糖尿病大鼠的心血管功能障碍
2. C16, a novel advanced glycation endproduct breaker, restores cardiovascular dysfunction in experimental diabetic rats [J] . Gang CHENG, Li-li WANG, Wen-sheng QU, 中国药理学报：英文版 . 2005,第012期

机译：C16是一种新型的先进糖基化终末阻断剂，可恢复实验性糖尿病大鼠的心血管功能障碍
3. Beneficial effects of Chinese prescription Kangen-karyu on diabetes associated with hyperlipidemia, advanced glycation endproducts, and oxidative stress in streptozotocin-induced diabetic rats. [J] . Kim HY, Okamoto T, Yokozawa T Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2009,第2期

机译：中药抗根方对链脲佐菌素诱发的糖尿病大鼠高脂血症，糖基化终末产物和氧化应激相关糖尿病的有益作用。
4. THE MAILLARD REACTION - A JOURNEY FROM THE DISCOVERY OF ADVANCED GLYCATION ENDPRODUCTS TO THEIR CHIEF CELLULAR RECEPTOR, RAGE: A MECHANISM UNDERLYING DIABETIC COMPLICATIONS AND THE INFLAMMATORY RESPONSE [C] . R. Ramasamy, S.F. Yan, A.M. Schmidt International Symposium on the Maillard Reaction . 2010

机译：毛利德反应 - 从先进的糖化封端到其主要细胞受体的旅程，愤怒：糖尿病并发症的机制和炎症反应
5. Investigating the role of advanced glycation endproducts and the NADPH oxidase in diabetic vascular disease. [D] . Whalin, Matthew K. 2008

机译：研究晚期糖基化终产物和NADPH氧化酶在糖尿病血管疾病中的作用。
6. Lysozyme enhances renal excretion of advanced glycation endproducts in vivo and suppresses adverse age-mediated cellular effects in vitro: a potential AGE sequestration therapy for diabetic nephropathy? [O] . F. Zheng, W. Cai, T. Mitsuhashi, 2001

机译：溶菌酶在体内增强晚期糖基化终产物的肾脏排泄并在体外抑制年龄介导的不利细胞作用：糖尿病肾病的潜在年龄固存疗法？
7. Beneficial effects of C36, a novel breaker of advanced glycation endproducts cross-links, on the cardiovascular system of diabetic rats [O] . Cheng, G, Wang, L-L, Long, L, 2007

机译：新型糖基化终产物交联剂C36对糖尿病大鼠心血管系统的有益作用

Beneficial effects of C36 a novel breaker of advanced glycation endproducts cross-links on the cardiovascular system of diabetic rats

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