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Air pollution and doctors house calls for respiratory diseases in the Greater Paris area (2000–3)

机译:大巴黎地区的空气污染和医生之家呼吁呼吸系统疾病(2000-3年)

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摘要

This study describes the short‐term relationships between the daily levels of PM10, PM2.5, NO2 and the number of doctors' house calls for asthma, upper respiratory diseases (URD) and lower respiratory diseases (LRD) in Greater Paris for the years 2000–3. Doctors' house calls are a relevant health indicator for the study of short‐term health effects of air pollution. Indeed, it is potentially more sensitive than indicators such as general hospital admissions due to the severity of diseases motivating the call. In this study, time‐series analysis was used. The daily numbers of doctor's house calls were adjusted for time trends, seasonal factors, day of the week, influenza, weather and pollen. Up to 15 days of lag between exposure and health effects was considered using distributed lag models. A total of about 1 760 000 doctors' house calls for all causes occurred during the study period, among which 8027 were for asthma, 52 928 for LRD and 74 845 for URD. No significant increase in risk was found between air pollution and doctors' house calls for asthma. No significant association was found between NO2 and doctors' house calls. An increase of 10 μg/m3 in the mean levels of PM10 and PM2.5 encountered during the 3 previous days was associated with an increase of 3% (0.8% and 5.3%) and 5.9% (2.9% and 9.0%) in the number of doctor's house calls for URD and LRD, respectively. Considering up to 15 days between exposure and health outcomes, effects persist until 4 days after exposure and then decrease progressively. No morbidity displacement was observed. This study shows a significant heath effect of ambient particles (PM2.5 and PM10). When compared to the RRs obtained for mortality or hospital admissions in the same area, the values of the RRs obtained in this study confirm the higher sensibility of doctor's house calls for respiratory diseases as a health indicator.
机译:这项研究描述了多年来大巴黎地区每日PM10,PM2.5,NO2水平与医生诊治哮喘,上呼吸道疾病(URD)和下呼吸道疾病(LRD)的次数之间的短期关系。 2000–3。医生的上门服务是研究空气污染对健康的短期影响的相关健康指标。的确,由于疾病的严重性可能导致这种疾病比一般医院住院等指标更为敏感。在这项研究中,使用了时间序列分析。根据时间趋势,季节因素,星期几,流行性感冒,天气和花粉调整了医生的每日上门服务次数。使用分布式滞后模型考虑了暴露与健康影响之间长达15天的滞后。在研究期间,总计约有1 760 000名医生因各种原因上门诊治,其中哮喘8027例,LRD 52 928和URD 74 845。空气污染与医生呼吁哮喘的风险没有显着增加。在二氧化氮和医生的家中电话之间没有发现明显的关联。前三天遇到的PM10和PM2.5平均水平增加10μg/ m 3 分别与3%(0.8%和5.3%)和5.9%(分别有2.9%和9.0%的医生上门拜访URD和LRD。考虑到接触和健康结果之间的间隔长达15天,这种影响会持续到接触后4天,然后逐渐降低。没有观察到发病率移位。这项研究显示了周围颗粒(PM2.5和PM10)的显着健康效应。与在同一地区获得的死亡率或住院患者的RR相比,本研究中获得的RR值证实了医生将呼吸道疾病作为健康指标的敏感性更高。

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