The Uptake and Localization of Tetracycline in Human Blood Cells

摘要

The uptake of tetracycline by human blood cells has been investigated by means of fluorescence microscopy. The intense yellow fluorescence characteristic of the drug was found only in the leucocytes; the erythrocytes appeared uniformly dark. In both lymphocytes and polymorphonuclear leucocytes the nucleus exhibited more intense fluorescence than the cytoplasm. The importance of these results is discussed.