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Clinical Diagnostic Accuracy in the Management of Primary Stage 1 Cutaneous Malignant Melanoma in a Plastic Surgery Unit

机译:整形外科部门治疗原发性第1阶段恶性黑色素瘤的临床诊断准确性

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摘要

In a retrospective review of 614 primary Stage I cutaneous malignant melanomata and 40 nonmelanoma lesions, the diagnostic accuracy(DA) for malignant melanoma was 86.2%. A positive preoperative clinical diagnosis of malignant melanoma was confirmed histologically in 564/604 (93.3%) of lesions. For 614 histologically proven malignant melanomata a correct pre-operative clinical diagnosis had been made in 564/614 (91.9%).An additional 172 patients were referred for wider excisional surgery within 3 months of a biopsy elsewhere. For the total 786 (614+172) patients, the incidence of biopsy of a clinicially unsuspected (but subsequently histologically proven) malignant melanoma prior to referral to the Plastic Surgery Unit was lowest for lesions of the head and neck (18.3%) and lower limb (19.0%), and highest (almost half of the patients) for lesions of the hands and fingers.Previous reports of the poor level of clinical diagnostic accuracy in cutaneous malignant melanoma have not been confirmed in the present study.
机译:在对614例原发性I期皮肤恶性黑色素瘤和40例非黑色素瘤病变的回顾性回顾中,恶性黑色素瘤的诊断准确性(DA)为86.2%。 564/604(93.3%)的组织学证实为恶性黑色素瘤的术前临床阳性诊断。对于614例经组织学证实的恶性黑色素瘤,在564/614例中进行了正确的术前临床诊断(91.9%)。另有172例患者在其他地方进行活检后3个月内被转诊接受更广泛的切除术。对于总共786例(614 + 172)患者,在转诊至整形外科之前,临床上未经怀疑(但经过组织学证实)的恶性黑色素瘤的活检发生率在头颈部病变中最低(18.3%),并且更低肢体(19.0%),手部和手指病变最高(几乎一半的患者)。本研究尚未证实以前关于皮肤恶性黑色素瘤临床诊断准确性差的报道。

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