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Synergistic oligodeoxynucleotide strongly promotes CpG-induced interleukin-6 production

机译：协同寡聚脱氧核苷酸强烈促进CpG诱导的白介素6的产生

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BackgroundBacterial genomes span a significant portion of diversity, reflecting their adaptation strategies; these strategies include nucleotide usage biases that affect chromosome configuration. Here, we explore an immuno-synergistic oligodeoxynucleotide (iSN-ODN, named iSN34), derived from Lactobacillus rhamnosus GG (LGG) genomic sequences, that exhibits a synergistic effect on immune response to CpG-induced immune activation.

机译：背景细菌基因组的多样性很大，反映了它们的适应策略。这些策略包括影响染色体配置的核苷酸使用偏倚。在这里，我们探索一种免疫协同的寡脱氧核苷酸（iSN-ODN，命名为iSN34），其来源于鼠李糖乳杆菌GG（LGG）基因组序列，对CpG诱导的免疫激活的免疫应答具有协同作用。

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期刊名称 BMC Immunology
作者
Shireen Nigar; Yoshinari Yamamoto; Takuma Okajima; Suguru Shigemori; Takashi Sato; Tasuku Ogita; Takeshi Shimosato;
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作者单位

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年(卷),期 2017(18),-1
年度 2017
页码 44
总页数 9
原文格式 PDF
正文语种
中图分类免疫学;
关键词
LGG CpG-ODN iSN-ODN IL-6 Synergistic effect;

机译：LGG;CpG-ODN;iSN-ODN;IL-6;协同效应;
入库时间 2022-08-17 14:23:28

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专利

1. Synergistic oligodeoxynucleotide strongly promotes CpG-induced interleukin-6 production [J] . Shireen Nigar, Yoshinari Yamamoto, Takuma Okajima, BMC Immunology . 2017,第1期

机译：协同寡聚脱氧核苷酸强烈促进CpG诱导的白介素6的产生
2. Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production. [J] . Fang C, Zhang X, Miwa T Blood: The Journal of the American Society of Hematology . 2009,第5期

机译：补体通过与Toll样受体信号传导和白介素6产生的协同相互作用促进炎性T辅助17细胞的发育。
3. Interleukin-6 and insulin-like growth factor-1 synergistically promote the progression of NSCLC [J] . Tang Hexiao, Bai Yuquan, Pan Gaofeng, Autoimmunity . 2018,第1a8期

机译：白细胞介素-6和胰岛素样生长因子-1协同促进NSCLC的进展
4. Production of nitric oxide, tumor necrosis factor-a and interleukin-6 by RAW264.7 macrophage cells treated with lactic acid bacteria isolated from kimchi [C] . Haeng Jeon Hur, Ki Won Lee, Hyong Joo Lee International Conference on Food Factors . 2004

机译：用乳酸菌分离的乳酸菌治疗的Raw264.7巨噬细胞生产一氧化氮，肿瘤坏死因子-A和白细胞介素-6
5. gamma-Aminobutyric acid inhibits cytokine-mediated synergistic induction of astrocytic interleukin-6 release: A mechanistic study. [D] . Aguinaldo, Grant Toshio. 2006

机译：γ-氨基丁酸抑制细胞因子介导的星形胶质细胞白细胞介素6释放的协同诱导：一项机理研究。
6. Immunobiology: Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production [O] . Chongyun Fang, Xinhua Zhang, Takashi Miwa, -1

机译：免疫生物学：补体通过与Toll样受体信号传导和白介素6产生协同相互作用促进炎症性T辅助17细胞的发育。
7. Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production [O] . Fang, Chongyun, Zhang, Xinhua, Miwa, Takashi, 2009

机译：补体通过与Toll样受体信号传导和白介素6产生的协同相互作用促进炎性T辅助17细胞的发育。
8. Synergistic Roles of Interleukin-6, Interleukin-1, and Tumor Necrosis Factor inthe Adrenocorticotropin Response to Bacterial Lipopolysaccharide In vivo [R] . Perlstein, R. S., Whitnall, M. H., Abrams, J. S., 1993

机译：白细胞介素-6，白细胞介素-1和肿瘤坏死因子在促肾上腺皮质激素对体内细菌脂多糖反应中的协同作用

Synergistic oligodeoxynucleotide strongly promotes CpG-induced interleukin-6 production

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