Antiaging effect of a Jianpi-yangwei formula in Caenorhabditis elegans

摘要

Effect of JPYW on the lifespan of N2 worms under normal conditions. The worms were treated with JPYW beginning at the larval stage. The curves show the percentages of surviving worms on different days after treatment with a vehicle control (1% DMSO) or 150 μg/ml JPYW. JPYW did not significantly prolong the lifespan of wild-type worms, but it caused a positive trend in the number of surviving aged worms (  = 50). The aged worms were exposed to JPYW beginning on the 7th day of adulthood. The curves show the percentages of surviving worms on different days after treatment with a vehicle control (1% DMSO) or 150 μg/ml JPYW. JPYW significantly prolonged the lifespan of aged wild-type worms; n = 50–51,