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Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model

机译：作为细胞脂肪变性模型Oligonol抑制棕榈酸诱导的HepG2肝细胞中脂质的积累并改善胰岛素抵抗。

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摘要

BackgroundOligonol is a low molecular weight form of polyphenol polymers derived from lychee fruits. Several studies suggest that Oligonol has an anti-obesity effect. Since obesity is tightly associated with insulin resistance, we investigated a possible remission effect of Oligonol on lipid accumulation and insulin resistance in human hepatic HepG2 cells.

机译：背景寡酚是衍生自荔枝果实的低分子量形式的多酚聚合物。多项研究表明，低聚木酚具有抗肥胖作用。由于肥胖与胰岛素抵抗密切相关，因此我们研究了低聚酚对人肝HepG2细胞脂质积累和胰岛素抵抗的可能缓解作用。

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期刊名称 BMC Complementary and Alternative Medicine
作者
Jae-Yeo Park; Younghwa Kim; Jee Ae Im; Hyangkyu Lee;
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作者单位

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年(卷),期 2015(15),-1
年度 2015
页码 185
总页数 13
原文格式 PDF
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关键词
Oligonol Hepatic steatosis de novo fatty acid synthesis Inflammation Insulin resistance;

机译：寡酚;肝脂肪变性;从头合成脂肪酸;炎症;胰岛素抵抗;

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专利

1. Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model [J] . Jae-Yeo Park, Younghwa Kim, Jee Ae Im, BMC Complementary and Alternative Medicine . 2015,第1期

机译：作为细胞脂肪变性模型，Oligonol抑制棕榈酸诱导的HepG2肝细胞中的脂质蓄积并改善胰岛素抵抗。
2. Paeoniflorin suppresses lipid accumulation and alleviates insulin resistance by regulating the Rho kinase/IRS-1 pathway in palmitate-induced HepG2Cells [J] . Ma Zhihong, Liu Hongying, Wang Weijie, Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie . 2017,第期

机译：Paeoniflorin抑制脂质积累，通过调节棕榈酸诱导的HepG2Cells的Rho激酶/ IRS-1途径来减轻胰岛素抵抗力
3. Supplementation with Vitis vinifera L. skin extract improves insulin resistance and prevents hepatic lipid accumulation and steatosis in high-fat diet-fed mice [J] . Nutrition Research . 2017,第期

机译：患有血管血管剂L.皮肤提取物提高了胰岛素抵抗力，可防止高脂饮食喂养小鼠中的肝脂积累和脂肪变性
4. Intramyocellular lipid accumulation and insulin resistance development [C] . C. Aguer, J. Mercier, C. Yong Wai Man, International Symposium on Energy and Protein Metabolism and Nutrition . 2007

机译：肌内粒细胞脂质积累和胰岛素抗性发育
5. Conjugated linoleic acid (CLA) in liver and adipose metabolism: Effects on insulin resistance, adiposity, lipidemia and hepatic steatosis in fa/fa and lean Zucker rats. [D] . Noto, Amy Dianne. 2005

机译：肝脏和脂肪代谢中的共轭亚油酸（CLA）：对fa / fa和lean Zucker大鼠的胰岛素抵抗，肥胖，血脂异常和肝脂肪变性的影响。
6. Quercetin improves insulin resistance and hepatic lipid accumulation in vitro in a NAFLD cell model [O] . XIULI LI, RONG WANG, NA ZHOU, -1

机译：槲皮素在NAFLD细胞模型中改善胰岛素抵抗和肝脂质蓄积
7. Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model [O] . 2015

机译：作为细胞脂肪变性模型，Oligonol抑制棕榈酸诱导的HepG2肝细胞中脂质的积累并改善胰岛素抵抗。

Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model

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