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Brazilin isolated from Caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse model

机译：从Caesalpinia sappan L.分离的Brazilin在II型胶原诱导的关节炎小鼠模型中抑制类风湿关节炎活性

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摘要

BackgroundCaesalpinia sappan L. extracts exhibit great therapeutic potential, and have been shown to have analgesic and anti-inflammatory properties. This study aimed to understand the anti-rheumatoid activity of brazilin that was isolated from ethyl acetate extract of C. sappan L. The evaluations were conducted in mice with type-II collagen-induced arthritis (CIA).

机译：背景es槐Ca提取物显示出巨大的治疗潜力，并已显示具有镇痛和抗炎特性。这项研究旨在了解从C. sappan L的乙酸乙酯提取物中分离出来的巴西灵芝的抗类风湿活性。在患有II型胶原诱导的关节炎（CIA）的小鼠中进行了评估。

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期刊名称 BMC Complementary and Alternative Medicine
作者
Eui-Gil Jung; Kook-Il Han; Seon Gu Hwang; Hyun-Jung Kwon; Bharat Bhusan Patnaik; Yong Hyun Kim; Man-Deuk Han;
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作者单位

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年(卷),期 2015(15),-1
年度 2015
页码 124
总页数 11
原文格式 PDF
正文语种
中图分类
关键词
Caesalpinia sappan Rheumatoid arthritis Collagen-induced arthritis Brazilin Pro-inflammatory cytokines;

机译：es骨;类风湿性关节炎;胶原蛋白诱发的关节炎;Brazalin;促炎细胞因子;

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专利

1. Brazilin from Caesalpinia sappan heartwood and its pharmacological activities:A review [J] . Nilesh P Nirmal, Mithun S Rajput, Rangabhatla GSV Prasad, 亚太热带生物医学杂志（英文版） . 2015 ,第006期
2. Brazilin from Caesalpinia sappan heartwood and its pharmacological activities: A review [J] . Nilesh P Nirmal, Mithun S Rajput, Rangabhatla G.S.V.Prasad, 亚太热带医药杂志（英文版） . 2015 ,第006期
3. Brazilin isolated from Caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse model [J] . Eui-Gil Jung, Kook-Il Han, Seon G Hwang, BMC Complementary and Alternative Medicine . 2015 ,第1期

机译：从Caesalpinia sappan L.分离的Brazilin在II型胶原诱导的关节炎小鼠模型中抑制类风湿关节炎活性
4. Anti-inflammatory activity of sappanchalcone isolated from Caesalpinia sappan L. in a collagen-induced arthritis mouse model [J] . Jung Eui-Gil, Han Kook-Il, Kwon Hyun-Jung, Archives of pharmacal research . 2015 ,第6期

机译：胶原诱导的关节炎小鼠模型中从凯撒pin中分离出的沙潘查尔酮的抗炎活性
5. Extract of the dried heartwood of Caesalpinia sappan L. attenuates collagen-induced arthritis. [J] . Wang YZ, Sun SQ, Zhou YB Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2011 ,第1期

机译：es子干心材的提取物可减轻胶原蛋白诱发的关节炎。
6. Iron chelating activity of Caesalpinia sappan L. extract on iron status in iron overload rats (Rattus norvegicus L.) [C] . Ratu Safitri, Ani Melani Maskoen, Mas Rizky Anggun Adipurna Syamsunarno, International Conference on Biological Science . 2018

机译：CaeSalpinia Sappan L. Irner in Iron Rover荷兰大鼠铁路螯合螯合剂（rattus norvegicus l.）
7. Vaccinia virus complement control protein ameliorates collagen induced arthritis: Potential implications for therapy of rheumatoid arthritis. [D] . Jha, Purushottam. 2003

机译：牛痘病毒补体控制蛋白可改善胶原蛋白诱发的关节炎：类风湿关节炎的治疗潜力。
8. Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells responses [O] . Hung-Bo Hsiao, Chang-Chi Hsieh, Jin-Bin Wu, 2016

机译：Kinsenoside通过调节T细胞反应来抑制II型胶原诱导的关节炎小鼠模型中炎性介质的释放
9. Brazilin isolated from Caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse model [O] . Eui-Gil Jung, Kook-Il Han, Seon Gu Hwang, 2015

机译：从Caesalpinia sappan L.分离的Brazilin在II型胶原诱导的关节炎小鼠模型中抑制类风湿关节炎活性

Brazilin isolated from Caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse model

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