LncRNA MALAT1 exhibits positive effects on nucleus pulposus cell biology in vivo and in vitro by sponging miR-503

摘要

The expression of MALAT1 in lumbar IDD tissues and the correlation with prognosis of IDD MALAT1 expression in 10 normal and 37 IDD tissue specimens determined by real-time PCR assays. MALAT1 expression in 37 IDD tissue specimens was delineated according to the Pfirrmann grading groups (mild  = 21, severe  = 16). – The mRNA expression of IL-1β, Collagen II and Aggrecan in 10 normal and 37 IDD tissue specimens was determined using real-time PCR assays. The data are presented as mean ± SD of three independent experiments