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A phase II study of Osimertinib for patients with radiotherapy-naïve CNS metastasis of non-small cell lung cancer: treatment rationale and protocol design of the OCEAN study (LOGIK 1603/WJOG 9116L)

机译：Osimertinib的II期研究用于非小细胞肺癌未经放射治疗的中枢神经系统转移的患者：OCEAN研究的治疗原理和方案设计（LOGIK 1603 / WJOG 9116L）

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Study schema

机译：学习模式

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期刊名称 BMC Cancer
作者
Kazushige Wakuda; Hiroyuki Yamaguchi; Hirotsugu Kenmotsu; Minoru Fukuda; Masafumi Takeshita; Takayuki Suetsugu; Keisuke Kirita; Noriyuki Ebi; Osamu Hataji; Satoru Miura; Kenji Chibana; Isamu Okamoto; Kenichi Yoshimura; Kazuhiko Nakagawa; Nobuyuki Yamamoto; Kenji Sugio;
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年(卷),期 2020(20),-1
年度 2020
页码 -1
总页数 6
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Non-small cell lung cancer; EGFR T790M; CNS metastasis; Brain metastasis; Osimertinib;

机译：非小细胞肺癌;EGFR T790M;中枢神经系统转移;脑转移;奥西替尼;

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专利

1. A phase II study of Osimertinib for patients with radiotherapy-na?ve CNS metastasis of non-small cell lung cancer: treatment rationale and protocol design of the OCEAN study (LOGIK 1603/WJOG 9116L) [J] . Kazushige Wakuda, Hiroyuki Yamaguchi, Hirotsugu Kenmotsu, BMC Cancer . 2020,第1期

机译：非小细胞肺癌放射治疗 - NA ve患者患者的II期研究：海洋研究的治疗理由和协议设计（Logik 1603 / Wjog 9116L）
2. A randomized phase II study of S-1 monotherapy versus cisplatin with vinorelbine for completely resected stage II/IIIA non-small cell lung cancer: rationale and study protocol design for the LOGIK1702 study [J] . Tomoshi Tsuchiya, Keitaro Matsumoto, Takuro Miyazaki, BMC Cancer . 2021,第1期

机译：S-1单疗法的随机阶段II研究与血红素素完全切除阶段II / IIIA非小细胞肺癌的血红蛋白：Logik1702研究的理由和研究方案设计
3. A Randomized Phase II Study Comparing Nivolumab With Carboplatin-Pemetrexed for Patients With EGFR Mutation–Positive Nonsquamous Non–Small-Cell Lung Cancer Who Acquire Resistance to Tyrosine Kinase Inhibitors Not Due to a Secondary T790M Mutation: Rationale and Protocol Design for the WJOG8515L Study [J] . Hidetoshi Hayashi, Yasutaka Chiba, Kazuko Sakai, Clinical lung cancer . 2017,第6期

机译：随机期II研究将Nivolumab与Carboplatin-Pemetrexed进行比较，用于EGFR突变阳性非小细胞肺癌患者，他捕获酪氨酸激酶抑制剂的抗性不是由于次级T790M突变：WJOG8515L研究的理由和协议设计
4. The clinical efficacy of transfusion of cytokine-induced killer cells combined with chemotherapy and XiaoJi decoction in patients with stage IIIB/IV non-small cell lung cancer [C] . Liuning Li, Jiaying Liu, Xiaoshu Chai, IEEE International Conference on Bioinformatics and Biomedicine . 2014

机译：细胞因子诱导的杀伤细胞输注结合化学疗法和消积汤治疗IIIB / IV期非小细胞肺癌的临床疗效
5. Assessing the effectiveness of palliative chemotherapy for non-small cell lung cancer: A phase IV study of patients treated at Ontario's cancer centres [D] . Harrison, Lyndsay Dawn. 2012

机译：评估姑息化疗对非小细胞肺癌的有效性：在安大略省癌症中心接受治疗的患者的IV期研究
6. A randomized phase II study of S-1 monotherapy versus cisplatin with vinorelbine for completely resected stage II/IIIA non-small cell lung cancer: rationale and study protocol design for the LOGIK1702 study [O] . Tomoshi Tsuchiya, Keitaro Matsumoto, Takuro Miyazaki, 2021

机译：S-1单疗法的随机阶段II研究与血管内的血红素素完全切除阶段II / IIIA非小细胞肺癌：Logik1702研究的理由和研究方案设计
7. A randomized phase II study of S-1 monotherapy versus cisplatin with vinorelbine for completely resected stage II/IIIA non-small cell lung cancer: rationale and study protocol design for the LOGIK1702 study [O] . Tomoshi Tsuchiya, Keitaro Matsumoto, Takuro Miyazaki, 2021

机译：S-1单疗法的随机阶段II研究与血管内的血红素素完全切除阶段II / IIIA非小细胞肺癌：Logik1702研究的理由和研究方案设计

A phase II study of Osimertinib for patients with radiotherapy-naïve CNS metastasis of non-small cell lung cancer: treatment rationale and protocol design of the OCEAN study (LOGIK 1603/WJOG 9116L)

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