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Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor

机译:使用现成的传感器在人颞骨中进行差分耳蜗内声压测量

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摘要

The standard method to determine the output level of acoustic and mechanical stimulation to the inner ear is measurement of vibration response of the stapes in human cadaveric temporal bones (TBs) by laser Doppler vibrometry. However, this method is reliable only if the intact ossicular chain is stimulated. For other stimulation modes an alternative method is needed. The differential intracochlear sound pressure between scala vestibuli (SV) and scala tympani (ST) is assumed to correlate with excitation. Using a custom-made pressure sensor it has been successfully measured and used to determine the output level of acoustic and mechanical stimulation. To make this method generally accessible, an off-the-shelf pressure sensor (Samba Preclin 420 LP, Samba Sensors) was tested here for intracochlear sound pressure measurements. During acoustic stimulation, intracochlear sound pressures were simultaneously measurable in SV and ST between 0.1 and 8 kHz with sufficient signal-to-noise ratios with this sensor. The pressure differences were comparable to results obtained with custom-made sensors. Our results demonstrated that the pressure sensor Samba Preclin 420 LP is usable for measurements of intracochlear sound pressures in SV and ST and for the determination of differential intracochlear sound pressures.
机译:确定对内耳的声音和机械刺激的输出水平的标准方法是通过激光多普勒振动法测量人尸体颞骨(TBs)中骨的振动响应。但是,仅当完整的听骨链受到刺激时,该方法才是可靠的。对于其他刺激模式,需要替代方法。假定前庭sc骨(SV)和鼓室sc(ST)之间的耳蜗内声压差与激发相关。使用定制的压力传感器已成功对其进行了测量,并用于确定声音和机械刺激的输出水平。为了使该方法普遍可用,此处对现成的压力传感器(Samba Preclin 420 LP,Samba传感器)进行了耳蜗内声压测量。在声音刺激过程中,该传感器可同时测量SV和ST的耳蜗内声压,范围为0.1至8 kHz,且具有足够的信噪比。压力差可与定制传感器获得的结果相媲美。我们的结果表明,压力传感器Samba Preclin 420 LP可用于测量SV和ST中的耳蜗内声压以及确定差分耳蜗内声压。

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