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Differential Intracochlear Sound Pressure Measurements in Human Temporal Bones with an Off-the-Shelf Sensor

机译:具有搁板传感器的人体颞骨中的差分腹膜孔声压测量

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摘要

The standard method to determine the output level of acoustic and mechanical stimulation to the inner ear is measurement of vibration response of the stapes in human cadaveric temporal bones (TBs) by laser Doppler vibrometry. However, this method is reliable only if the intact ossicular chain is stimulated. For other stimulation modes an alternative method is needed. The differential intracochlear sound pressure between scala vestibuli (SV) and scala tympani (ST) is assumed to correlate with excitation. Using a custom-made pressure sensor it has been successfully measured and used to determine the output level of acoustic and mechanical stimulation. To make this method generally accessible, an off-the-shelf pressure sensor (Samba Preclin 420 LP, Samba Sensors) was tested here for intracochlear sound pressure measurements. During acoustic stimulation, intracochlear sound pressures were simultaneously measurable in SV and ST between 0.1 and 8 kHz with sufficient signal-to-noise ratios with this sensor. The pressure differences were comparable to results obtained with custom-made sensors. Our results demonstrated that the pressure sensor Samba Preclin 420 LP is usable for measurements of intracochlear sound pressures in SV and ST and for the determination of differential intracochlear sound pressures.
机译:来确定声学和机械刺激内耳的输出电平的标准方法是通过激光多普勒vibrometry在人类尸体颞骨(TBS)镫骨的振动响应的测量。然而,这种方法是可靠的只有完整的听骨链的刺激。对于其它的刺激模式,需要一种替代方法。耳蜗内前庭阶(SV)和鼓阶(ST)之间的声压的差被假定为与励磁相关。使用定制的压力传感器已经成功地测量并用于确定声学和机械刺激的输出电平。为了使这种方法通常可访问的,断开的,现成的压力传感器(桑巴Preclin 420 LP,桑巴传感器)在这里测试耳蜗内的声压测量。期间的声刺激,耳蜗内的声压是同时测量在SV和ST 0.1和8 kHz的具有足够的信号 - 噪声比与该传感器之间。压力差异与用定做的传感器获得的结果。我们的研究结果表明,传感器的Samba Preclin 420 LP的压力是用于SV和ST和用于差分耳蜗内声压的测定耳蜗内声压的测量结果可用。

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