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Remote Magnetic versus Manual Navigation for Radiofrequency Ablation of Paroxysmal Atrial Fibrillation: Long-Term, Controlled Data in a Large Cohort

机译:遥控消融与手动导航治疗阵发性心房颤动的射频消融:大型队列中的长期受控数据

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摘要

Purpose. We aimed to study long-term outcome after pulmonary vein isolation (PVI) guided by remote magnetic navigation (RMN) and provided comparative data to outcome after manual navigation (MAN). Methods. Three hundred thirty-six patients with symptomatic paroxysmal AF underwent PVI by irrigated point-by-point radiofrequency (RF) ablation (RMN, n = 114 versus MAN, n = 222). Patients were followed up with symptom guided rhythm monitoring for a period up to 43 months. The end point of the study was freedom from repeat ablation after a single procedure and without antiarrhythmic drug treatment (ADT). Results. At the end of follow-up (median 26.3 months), freedom from repeat ablation was comparable between RMN and MAN (70.9% versus 69.5%, p = 0.61). At repeat, mean number of reconnected veins was 2.4 ± 1.2 in RMN versus 2.6 ± 1.0 in MAN (p = 0.08). The majority of repeat procedures occurred during the first year (82.1% in RMN versus 78.5% in MAN; p = 0.74). Conclusion. On the long term (up to 3 years) and in a large cohort of patients with paroxysmal AF, RMN-guided PVI is as effective as MAN guided PVI. In both strategies the majority of repeat procedures occurred during the first year after index procedure.
机译:目的。我们旨在研究在远程磁导航(RMN)指导下进行肺静脉隔离(PVI)后的长期结局,并为手动导航(MAN)后的结局提供比较数据。方法。症状性阵发性房颤的366例患者接受了逐点射频(RFN)冲洗消融术(PNP,n = 114 vs MAN,n = 222)。对患者进行症状指导的心律监测,随访时间长达43个月。该研究的目的是在单次手术后无需抗心律不齐药物治疗(ADT)的情况下避免重复消融。结果。在随访结束时(中位26.3个月),RMN和MAN之间免于重复消融的自由度相当(70.9%对69.5%,p = 0.61)。重复一次,在RMN中平均重新连接的静脉数为2.4±1.2,而在MAN中为2.6±1.0(p = 0.08)。大多数重复手术发生在第一年(RMN为82.1%,MAN为78.5%; p = 0.74)。结论。从长远来看(长达3年),在大量阵发性AF患者中,RMN指导的PVI与MAN指导的PVI一样有效。在这两种策略中,大多数重复程序都发生在索引程序后的第一年。

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