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Long-term experience with apremilast in patients with psoriatic arthritis: 5-year results from a PALACE 1–3 pooled analysis

机译：银屑病关节炎患者长期使用前兆莫斯特的经验：PALACE 1-3汇总分析的5年结果

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BackgroundThe efficacy and safety of apremilast were assessed in patients with psoriatic arthritis (PsA) in three phase III clinical trials with similar designs (PALACE 1, 2, and 3).

机译：背景技术在银屑病关节炎（PsA）患者的三项具有相似设计的III期临床试验（PALACE 1、2和3）中，评估了前者的疗效和安全性。

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期刊名称 Arthritis Research
作者
Arthur Kavanaugh; Dafna D. Gladman; Christopher J. Edwards; Georg Schett; Benoit Guerette; Nikolay Delev; Lichen Teng; Maria Paris; Philip J. Mease;
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作者单位

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年(卷),期 2019(21),-1
年度 2019
页码 118
总页数 8
原文格式 PDF
正文语种
中图分类外科学;
关键词
Apremilast Drug safety Psoriatic arthritis Treatment efficacy;

机译：菊粉;药物安全性;银屑病关节炎;治疗功效;

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专利

1. Long-term experience with apremilast in patients with psoriatic arthritis: 5-year results from a PALACE 1–3 pooled analysis [J] . Arthur Kavanaugh, Dafna D. Gladman, Christopher J. Edwards, Arthritis research & therapy. . 2019,第1期

机译：银屑病关节炎患者长期使用普瑞司特的经验：PALACE 1-3汇总分析的5年结果
2. LONG-TERM (UP TO 156 WEEKS) SAFETY PROFILE OF ORAL APREMILAST IN PATIENTS WITH PSORIATIC ARTHRITIS: POOLED ANALYSIS OF PALACE 1-3 [J] . Mease P. J., Gladman D. D., Gomez-Reino J. J., Clinical and experimental rheumatology . 2016,第4期

机译：周期性关节炎患者（最长156周）的口服止痛药的安全性概况：宫殿1-3的分析
3. Low rates of major adverse cardiac events, malignancies, and serious infections in subjects with psoriasis and psoriatic arthritis treated with apremilast for = 156 weeks: pooled analysis from the ESTEEM and PALACE 1-3 phase 3 trials [J] . Kavanaugh A., Augustin M., Lespessailles E., Scandinavian journal of rheumatology . 2018,第Suppla129期

机译：患有牛皮癣和银屑病关节炎的主要不良心脏事件，恶性肿瘤和严重感染的低率＆ = 156周：从尊敬和宫内汇集分析1-3期3阶段试验
4. Psoriatic arthritis Clinical improvement and correlation with hormone axes in etanercept-treated patients [C] . Fabiola Atzeni, Rainer H. Straub, Maurizio Cutolo, International Conference on the Neuroendocrine Immune Basis of the Rheumatic Diseases . 2010

机译：依托西普治疗患者患者临床改善及与激素轴相关性
5. A direct comparison of long-term hyaluronic acid and corticosteroid intra-articular injections for moderate arthritis in patients aged twenty-five to fifty years old [D] . Hogan, Allison 2011

机译：直接比较长期透明质酸和皮质类固醇关节内注射，适度关节炎，患者25至五十岁患者
6. Original article: Therapeutic benefit of apremilast on enthesitis and dactylitis in patients with psoriatic arthritis: a pooled analysis of the PALACE 1–3 studies [O] . Dafna D Gladman, Arthur Kavanaugh, Juan J Gómez-Reino, 2018

机译：原始文章：普瑞司特对银屑病关节炎患者的脑炎和齿根炎的治疗益处：PALACE 1-3研究的汇总分析
7. SAT0436 Durability of apremilast response in patients with psoriatic arthritis: long-term (208-week) results from the palace 1 trial [O] . A Kavanaugh, DD Gladman, JJ Gomez-Reino, 2017

机译：SAT0436银屑病关节炎患者的评分0436耐久性：长期（208周）的宫殿1试验结果

Long-term experience with apremilast in patients with psoriatic arthritis: 5-year results from a PALACE 1–3 pooled analysis

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