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Childhood Cryptosporidium infection among aboriginal communities in Peninsular Malaysia

机译:马来西亚半岛原住民社区儿童时期的隐孢子虫感染

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摘要

Cryptosporidium is a coccidian parasite that is prevalent worldwide, some species of which cause morbidity in both immunocompromised and immunocompetent individuals. The prevalence and predictors of Cryptosporidium infection, and its effect on nutritional status, have recently been explored among 276 children (141 boys and 135 girls, aged 2–15 years) in aboriginal (Orang Asli) villages in the Malaysian state of Selangor. Faecal smears were examined by the modified Ziehl–Neelsen staining technique while socio–economic data were collected using a standardized questionnaire. Nutritional status was assessed by anthropometric measurements. Cryptosporidium infection, which was detected in 7·2% of the aboriginal children, was found to be significantly associated with low birthweight (⩽2·5 kg), being part of a large household (with more than seven members) and prolonged breast feeding (>2 years). The output of a binary logistic regression confirmed that large household size was a significant predictor of Cryptosporidium infection (giving an odds ratio of 2·15, with a 95% confidence interval of 1·25–5·02). Cryptosporidium infection is clearly a public-health problem among the aboriginal children of Selangor, with person-to-person the most likely mode of transmission.
机译:隐孢子虫是一种球虫寄生虫,在世界范围内都很普遍,其中某些物种在免疫功能低下和有免疫能力的个体中都引起发病。最近,在马来西亚雪兰莪州的原住民(奥朗·阿斯利)村的276名儿童(141名男孩和135名女孩,年龄在2-15岁之间)中发现了隐孢子虫感染的发生率和预测因素,及其对营养状况的影响。粪便涂片检查采用改良的Ziehl-Neelsen染色技术进行检查,而社会经济数据则使用标准化问卷进行收集。营养状况通过人体测量法评估。在原住民儿童中,有7·2%的儿童发现了隐孢子虫感染,这与低出生体重(⩽2·5 kg),大家庭(成员超过7人)和长期母乳喂养明显相关(> 2年)。二元逻辑回归分析的结果证实,家庭规模大是隐孢子虫感染的重要预测指标(比值比为2·15,95%置信区间为1·25-5·02)。在雪兰莪州的土著儿童中,隐孢子虫感染显然是一个公共卫生问题,人与人之间最可能的传播方式。

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