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A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab

机译:Secukinumab治疗中度化脓性汗腺炎和牛皮癣1例

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摘要

Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab.
机译:化脓性Hidradenitis(HS)是顶泌腺疾病,引起慢性,反复发作和疼痛性炎症。这是一种令人不安的疾病,尽管有许多治疗方法可供选择,但在大多数情况下,这种反应通常无效,并且患者可能会出现许多身体和心理后遗症的复发。最近的数据表明,HS患者的白细胞介素(IL)-17血清水平升高。牛皮癣是一种慢性免疫介导的炎症性疾病,新证据显示Th17细胞在其发病机理中发挥作用,并具有抗IL-17抗体的治疗功效。我们介绍了一例银屑病和HS的患者,在两种情况下均成功用抗IL-17抗体治疗。这是苏金单抗治疗HS的首例病例报告。

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