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Insulin-like growth factor-1 overexpression increases long-term survival of posttrauma-born hippocampal neurons while inhibiting ectopic migration following traumatic brain injury

机译：胰岛素样生长因子-1的过表达增加了创伤后出生的海马神经元的长期存活率同时抑制了脑外伤后的异位迁移

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摘要

Summary of statistics for cell type and location of posttrauma-proliferated cells

机译：创伤后增殖细胞的细胞类型和位置统计摘要

著录项

期刊名称 Acta Neuropathologica Communications
作者
Erica L. Littlejohn; Danielle Scott; Kathryn E. Saatman;
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作者单位

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年(卷),期 2020(8),-1
年度 2020
页码 -1
总页数 15
原文格式 PDF
正文语种
中图分类
关键词
Cognitive flexibility; Controlled cortical impact; Dentate gyrus; Gliogenesis; Granule cell layer; Neurogenesis; Reversal learning;

机译：认知灵活性;可控的皮层撞击;齿状回;胶质发生;颗粒细胞层;神经发生;逆向学习;

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专利

1. Conditional Overexpression of Insulin-Like Growth Factor-1 Enhances Hippocampal Neurogenesis and Restores Immature Neuron Dendritic Processes After Traumatic Brain Injury [J] . Carlson Shaun W., Madathil Sindhu K., Sama Diana M., Journal of Neuropathology and Experimental Neurology: Official Journal of the American Association of Neuropathologists, Inc . 2014,第8期

机译：胰岛素样生长因子-1的条件过表达增强海马神经元发生并在创伤性脑损伤后恢复未成熟的神经元树突过程。
2. Central Infusion of Insulin-Like Growth Factor-1 Increases Hippocampal Neurogenesis and Improves Neurobehavioral Function after Traumatic Brain Injury [J] . Carlson Shaun W., Saatman Kathryn E. Journal of neurotrauma . 2018,第13期

机译：胰岛素样生长因子-1的中央输注增加了海马神经发生，并且在创伤后脑损伤后改善了神经兽性功能
3. Comparative signaling pathways of insulin-like growth factor-1 and brain-derived neurotrophic factor in hippocampal neurons and the role of the PI3 kinase pathway in cell survival. [J] . Zheng WH, Quirion R Journal of Neurochemistry: Offical Journal of the International Society for Neurochemistry . 2004,第4期

机译：海马神经元中胰岛素样生长因子-1和脑源性神经营养因子的比较信号通路以及PI3激酶通路在细胞存活中的作用。
4. Discovery and SAR of Thiazolidine-2,4-dione Analogues as Insulin-like Growth Factor-1 Receptor (IGF-1R) Inhibitors via Hierarchical Virtual Screening [C] . Xiaofeng Liu, Hua Xie, Cheng Luo, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：噻唑烷-2,4-二酮类似物作为胰岛素样生长因子-1受体（IGF-1R）抑制剂的发现和SAR通过分层虚拟筛选
5. Effects of cerebellar injury and insulin-like growth factor 1 administration on functional recovery in a rat model of traumatic brain injury. [D] . Reynolds, Laura Patricia Ruth. 2003

机译：小脑损伤和胰岛素样生长因子1的给药对脑外伤大鼠模型功能恢复的影响。
6. Conditional Overexpression of Insulin-Like Growth Factor-1 Enhances Hippocampal Neurogenesis and Restores Immature Neuron Dendritic Processes After Traumatic Brain Injury [O] . Shaun W. Carlson, Sindhu K. Madathil, Diana M. Sama, -1

机译：胰岛素样生长因子-1的条件过表达增强海马神经发生并在创伤性脑损伤后恢复未成熟的神经元树突过程。
7. Conditional Overexpression of Insulin-Like Growth Factor-1 Enhances Hippocampal Neurogenesis and Restores Immature Neuron Dendritic Processes After Traumatic Brain Injury [O] . Shaun W. Carlson, Sindhu K. Madathil, Diana M. Sama, 2014

机译：胰岛素样生长因子-1的条件过表达增强了海马神经发生并在创伤性脑损伤后恢复未成熟的神经元树突病程
8. Insulin-Like Growth Factor Binding Protein-1 Interacts with Integrins to Inhibit Insulin-Like Growth Factor-Induced Breast Cancer Growth and Migration [R] . Gross, J. M. 2003

机译：胰岛素样生长因子结合蛋白-1与整合素相互作用，抑制胰岛素样生长因子诱导的乳腺癌生长和迁移

Insulin-like growth factor-1 overexpression increases long-term survival of posttrauma-born hippocampal neurons while inhibiting ectopic migration following traumatic brain injury

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